Gastroesophageal Reflux Disease

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Gastroesophageal Reflux Disease

General Information

NEWS:

Acid Reflux Adds to COPD Complications "Chronic obstructive pulmonary disease (COPD) patients who also have acid reflux are twice as likely to experience COPD exacerbations, says a study in the October issue of the journal Chest."

ARTICLES:

JOURNAL ARTICLES:

Advantages and disadvantages of lumping together gastroesophageal reflux disease and dyspepsia. (Curr Opin Gastroenterol. 2006) "SUMMARY: Gastroesophageal reflux disease is a well defined disease which can be diagnosed objectively with endoscopy or 24-h pH/impedance monitoring with symptom association analysis. Functional dyspepsia is a functional disorder for which no objective test has yet been discovered. Treatment of gastroesophageal reflux disease is based on objectively identified abnormalities and highly effective. Treatment of functional dyspepsia is empiric and marginally effective. For these reasons, the lumping together of gastroesophageal reflux disease and functional dyspepsia is not to be advised."

Anatomy of reflux: A growing health problem affecting structures of the head and neck. (Anat Rec B New Anat. 2006)

Association Between Dinner-to-Bed Time and Gastro-Esophageal Reflux Disease (Am J Gastroenterol 2005)

Chronic Cough Due to Gastroesophageal Reflux Disease: ACCP Evidence-Based Clinical Practice Guidelines. (Chest. 2006)

Chronic inflammation: a common and important factor in the pathogenesis of neoplasia. (CA Cancer J Clin. 2006)

[Diagnosis of gastroesophageal reflux disease and dyspepsia] (Schweiz Rundsch Med Prax. 2006)

Evaluation of gastro-oesophageal flap valve is useful for diagnosing gastro-oesophageal reflux disease. (Aliment Pharmacol Ther. 2006)

Gastroesophageal flap valve is associated with gastroesophageal and gastropharyngeal reflux. (J Gastroenterol. 2006)

Gastroesophageal reflux and laryngopharyngeal reflux in patients with sleep-disordered breathing. (Otolaryngol Head Neck Surg. 2006)

Gastroesophageal reflux disease and irritable bowel syndrome: a common overlap syndrome. (Curr Gastroenterol Rep. 2006) "Symptoms of IBS are commonly encountered in GERD patients, and symptoms of GERD are not uncommon in IBS patients. GERD patients consistently report lower abdominal symptoms, which may be part of the spectrum of GERD symptoms."

Gastroesophageal Reflux Disease as a Cause of Death Is Increasing: Analysis of Fatal Cases After Medical and Surgical Treatment. (Am J Gastroenterol. 2006) "CONCLUSIONS: Regardless of the increased use of health resources, mortality from GERD, especially with medical treatment, rose. Surgery for GERD was also associated with early mortality and usually could not prevent the fatal outcome."

Gastroesophageal reflux disease (GERD), extraesophageal reflux (EER) and recurrent chronic rhinosinusitis. (Eur Arch Otorhinolaryngol. 2006) "Chronic polypoid rhinosinusitis (CRS) is a common disease, affecting approximately 16% of the adult population in the US every year. In addition to many well known predisposing factors, an association with reflux disease is hypothesized. Such an association might explain the recurrence of polyposis in the face of improved surgical techniques and postsurgical treatment of CRS. . Recurrent CRS is often associated with GERD but not with EER. Recurrent disease or prolonged recovery after surgery should raise the suspicion of reflux disease as a possible triggering factor. Because GERD itself cannot be diagnosed by laryngoscopy, and because of the subjectivity of symptoms such as heartburn, the otolaryngologist should consider double-probe pH testing as the diagnostic procedure of choice."

Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults. (Cochrane Database Syst Rev. 2006)

Helicobacter pylori seropositivity predicts outcomes of acid suppression therapy for laryngopharyngeal reflux symptoms. (Laryngoscope. 2006) "CONCLUSIONS: By focusing on the involvement of H. pylori infection in laryngopharyngeal reflux, we determined the relationships between H. pylori antibody positivity and response to acid-suppression therapy among patients. The laryngopharyngeal, not esophageal, symptom relief by acid-suppression therapy was significantly lower among H. pylori antibody-negative cases than among antibody-positive cases."

Is Esophageal Adenocarcinoma Occurring Late After Antireflux Surgery Due to Persistent Postoperative Reflux? (World J Surg. 2006) "CONCLUSIONS: Esophageal adenocarcinoma occurring late after antireflux surgery might at least partly be due to persistent postoperative reflux."

Is Gastroesophageal Reflux Disease Really a Life-Long Disease: Do Babies Who Regurgitate Grow up to Be Adults with GERD Complications? (The American Journal of Gastroenterology 2006)

Nonacid reflux in patients with chronic cough on Acid-suppressive therapy. (Chest. 2006)

Overlapping abdominal symptoms: Why do GERD and IBS often coexist? (Drugs Today (Barc). 2006) "Although GERD, dyspepsia and IBS are highly prevalent conditions, overlapping symptoms should be not be attributed to their high prevalence but to a possible common disease process in a subset of patients."

Role of Gastroesophageal Reflux Symptoms in Exacerbations of COPD. (Chest. 2006) "CONCLUSIONS: The presence of GER symptoms appears to be associated with increased exacerbations of COPD."

Studying the Overlap Between IBS and GERD: A Systematic Review of the Literature. (Dig Dis Sci. 2006) "Evidence points to a significant overlap between irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD). … The maximum mean prevalence of IBS in subjects with known GERD was 48.8% and the weighted mean 60.5%. Based on the prevalence of IBS (12.1%) and GERD (19.4%) in the community, the rate of IBS in the non-GERD community was calculated to be only 5.1%. There is a strong overlap between GERD and IBS that exceeds the individual presence of each condition. In the absence of GERD, IBS is relatively uncommon."

Systematic review and meta-analysis of randomised controlled trials of gastro-oesophageal reflux interventions for chronic cough associated with gastro-oesophageal reflux (BMJ 2006)

Systematic review on epidemiology of gastroesophageal reflux disease in Asia. (Clin Gastroenterol Hepatol. 2006) "In case studies, the prevalence of reflux esophagitis ranged from 3.4% to 16.3%. Well-established risk factors for GERD in Asian populations included hiatus hernia and obesity. Age and male sex also may be risk factors. Chest pain is the predominant extraesophageal manifestation of GERD in China, whereas in Japan, a link with asthma has been implicated in patients with severe esophagitis."

The Long-Term Natural History of Gastroesophageal Reflux Disease. (J Clin Gastroenterol. 2006)

The relation between gastroesophageal reflux and respiratory symptoms in a population-based study: the nord-trondelag health survey. (Chest. 2006) "CONCLUSIONS: Reflux symptoms commonly coexist with asthma and other respiratory symptoms on a population-based level, seemingly irrespective of asthma medication."

The role of gastric Helicobacter pylori infection in laryngopharyngeal reflux disease. (Otolaryngol Head Neck Surg. 2006)

[The roles of Helicobacter pylori and pattern of gastritis in the pathogenesis of reflux esophagitis] (honghua Yi Xue Za Zhi. 2006)

Time Trends of Gastroesophageal Reflux Disease: A Systematic Review. (Clin Gastroenterol Hepatol. 2006) "There is evidence that the prevalence of GERD has increased during the past 2 decades. If this trend continues, it could contribute to the rapidly increasing incidence of more serious complications associated with GERD, such as esophageal adenocarcinoma, as well as costs to healthcare systems and employers."

White wine and beer induce gastro-oesophageal reflux in patients with reflux disease. (Aliment Pharmacol Ther. 2006) "Conclusions Ingestion of commonly consumed alcoholic beverages such as wine and beer induces gastro-oesophageal reflux in gastro-oesophageal reflux disease patients. Therefore, these patients should be advised to avoid the intake of large amounts (>/=300 mL) of these beverages."

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