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Asthma

General Information

NEWS:

Asthma Boosts Odds for Other Chronic Health Woes

Asthma rates rise as kids get older "Some children who have asthma at age 7 are asthma-free by the time they reach 12, but the number of kids who go into remission is more than offset by the number who develop the condition during that age period, according to Swedish investigators."

Back-to-school asthma tips for parents

Dogs Plus Smog Bad for Asthmatic Kids

Family cat unlikely to give baby Johnny asthma

Health Tip: Asthmatics Often Have Pet Allergies

Mouse in the house may be hard on kids' asthma

Sharp Increase in Children's Asthma Rates

State of Childhood Asthma, United States: 1980-2005

ARTICLES:

Asthma

Asthma, Children And School

JOURNAL ARTICLES:

Airborne Pollen Concentrations and the Incidence of Allergic Asthma and Rhinoconjunctivitis in Northern Italy from 1992 to 2003. (Int Arch Allergy Immunol. 2006) "Conclusions: Significant correlations between the increasing incidence in asthma and allergy to mites, pets and birch pollen are shown. The decrease in the total pollen count and concentration peaks of grass pollen was correlated to the decreasing trend of rhinoconjunctivitis. The trend of increasing concentrations of ash-olive and ragweed pollen was not accompanied by an increase in the related allergy."

Allergic rhinitis and sinusitis in asthma: differential effects on symptoms and pulmonary function. (Chest. 2006) "CONCLUSION: Allergic rhinitis and sinusitis are associated with more severe asthmatic symptoms and, in patients with poorly controlled asthma, more exacerbations but are not associated with low lung function."

Ambient Air Pollution and Asthma Exacerbations in Children: An Eight-City Analysis (American Journal of Epidemiology 2006)

Association between leptin and asthma in adults (Thorax 2006)

Asthma in every fifth child in Oslo, Norway: a 10-year follow up of a birth cohort study*. (Allergy. 2006) "Results: Lifetime prevalence of asthma was 20.2%; current asthma 11.1%, doctor diagnosis of asthma 16.1% and wheezes ever 30.3%. Allergic sensitization (29.3% overall) was more common among children with current (56.3%) compared to asymptomatic (last 12 months) (26.0%) or no asthma (27.6%) (P < 0.001). Boys more often than girls had current asthma (14.4 vs 7.1%, P = 0.004), wheeze ever (36.9 vs 22.5%, P = 0.002) and allergic sensitization (36.2 vs 22.1%, respectively, P < 0.001). Conclusion: Childhood asthma apparently continues to increase in Oslo, having affected every fifth 10-year-old child."

Behavior Problems Among Inner-City Children With Asthma: Findings From a Community-Based Sample (PEDIATRICS 2006)

Childhood obesity increases duration of therapy during severe asthma exacerbations (Pediatr Crit Care Med. 2006) "CONCLUSIONS:: Childhood obesity significantly affects the health of children with asthma. Obese children with status asthmaticus recovered more slowly from an acute exacerbation, even after adjustment for baseline asthma severity and admission severity of illness."

Chronic productive cough in school children: prevalence and associations with asthma and environmental tobacco smoke exposure. (Cough. 2006) " CONCLUSIONS: In a population of young teenagers, CPC was strongly associated with report of current asthma symptoms and also with ETS exposure. This suggests that asthma and ETS exposure may contribute to CPC in children."

[Current prevalence of asthma in schoolchildren in San Sebastian (Spain).] (An Pediatr (Barc). 2006) "RESULTS: The questionnaire of symptoms and signs compatible with asthma revealed a current prevalence of asthma of 25.56 % (n = 216) and a cumulative prevalence of 25.44 % (n = 85). Nocturnal asthma was found in 29.37 % (n = 47) and severe asthma in 9.27 % (n = 14). Bronchial hyperresponsiveness was found in 23 % of the participants. An epidemiological diagnosis of asthma (asthma-related symptoms plus bronchial hyperresponsiveness) was made in 6.54 %. CONCLUSIONS: The current prevalence of asthma in 6-12-year-old schoolchildren in San Sebastian, determined through symptoms and signs compatible with asthma in the previous year and a positive free running test, is similar to that reported in other national studies."

Encasement of bedding does not improve asthma in atopic adult asthmatics. (Int Arch Allergy Immunol. 2006) "CONCLUSIONS: Encasement of bedding significantly reduced the Der p 1 levels. However, this was not sufficient to produce worthwhile clinical improvement in those in whom dust mite avoidance might well have been recommended as part of their clinical management."

Epithelial Damage and Angiogenesis in the Airways of Children with Asthma. (Am J Respir Crit Care Med. 2006) "Conclusions. Epithelial damage and basement membrane thickening, which are pathologic features characteristic of adult asthma, are present even in childhood asthma. Other changes, such as airway eosinophilia and angiogenesis, were also observed in atopic children without asthma. These observations suggest that pathological changes occur early in the natural history of asthma and emphasize the concept that some of these lesions may characterize atopy even in the absence of asthmatic symptoms."

High body mass index and dietary pattern are associated with childhood asthma. (Pediatr Pulmonol. 2006) "These results indicate that BMI may be an independent risk factor for the development of asthma symptoms in boys. Intake of fresh seafood, fresh fruit, and vegetables, which may be associated with decreased BMI, may contribute to protect against the development of asthma symptoms in Korean elementary schoolchildren."

High sensitivity C-reactive protein in asthma. (Eur Respir J. 2006)

How does exercise cause asthma attacks? (Curr Opin Allergy Clin Immunol. 2006)

Implications of psychosocial factors as precipitant of asthma attack among a sample of asthmatics. (J Asthma. 2006)

Links between allergic rhinitis and asthma. (Chin Med J (Engl). 2006) "Allergic diseases of the airway, which include seasonal rhinitis, chronic perennial rhinitis and asthma, are recognized as inflammatory disorders of the airway mucosa,1-3 but differ in the location of the inflammatory reaction and clinical manifestations of the disease. Asthma and allergic rhinitis frequently coexist in the same patient and are thought to share common predisposing genetic factors which interact with the environmental influences. Both diseases have increased in prevalence over recent decades4,5 particularly in westernized countries. This increase has been largely attributed to environmental factors such as exposure to aerial pollutants,4,6 and early life events, including the degree of exposure to infectious agents which might affect IgE production,5,7 since there has been insufficient time for a significant change in the gene pool."

Nearly six million Californians suffer from asthma symptoms or asthma-like breathing problems. (Policy Brief UCLA Cent Health Policy Res. 2006) "In California, 4.5 million adults, adolescents and children had been diagnosed with asthma (13% of all Californians) in 2003, up from four million (12%) in 2001."

Predicting adult asthma in childhood. (Curr Opin Pulm Med. 2006)

Prognostic factors of asthma severity: A 9-year international prospective cohort study. (J Allergy Clin Immunol. 2006) "CONCLUSION: Patients with moderate and severe persistent asthma are characterized by early deterioration of lung function. High IgE levels and persistent cough/mucus hypersecretion are strong markers of moderate/severe asthma, which seems to be a different phenotype from mild persistent or intermittent asthma. CLINICAL IMPLICATIONS: Our results suggest that the evolution of asthma severity is to a large extent predictable."

Specific Molds Associated With Asthma in Water-Damaged Homes. (J Occup Environ Med. 2006) "RESULTS:: Two molds, Scopulariopsis brevicaulis and Trichoderma viride, had significantly (P < 0.05) higher concentrations in asthmatics' homes compared with control homes and three other molds (Penicillium crustosum group, Stachybotrys chartarum, and Wallemia sebi) had P values <0.1. CONCLUSIONS:: A relative moldiness index was developed to predict the likely development of asthma in water-damaged homes in Cleveland."

The natural history of asthma. (J Allergy Clin Immunol. 2006) "Asthma begins most often in infants as wheezing with respiratory infections. If these episodes are mild and infrequent, asthma does not usually persist into the school years. However, if they are more frequent and severe, the asthma is likely to persist. After infancy, incidence falls and continues at about 100/100,000 for the rest of the lifespan. Allergic asthma develops most often in the second decade of life and frequently persists into adult years, but young patients with allergic asthma often enjoy a transient or even a permanent remission. More severe disease and continued allergen exposure cause persistence. Some patients with occupational asthma continue to have asthma long after exposure ceases."

The relationship between the severity of asthma and comorbidites with anxiety and depressive disorders. (Rev Bras Psiquiatr. 2006) "CONCLUSIONS: Our results support the high morbidity of anxiety and depressive disorders in asthmatic patients, independent of the severity of asthma."

The Role of Sinus Disease in Asthma (Curr Opin Allergy Clin Immunol. 2006)

The September epidemic of asthma hospitalization: School children as disease vectors (Journal of Allergy and Clinical Immunology 2006)

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