Cancer - General

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Cancer - General

General Information

NEWS:

Annual Cancer Deaths in the U.S. Fall

Cancer Drug Ads Put Caveats in Fine Print " 'Direct-to-consumer advertising of oncology medications typically focuses on the drugs' benefits, as would be expected, but it does so in a manner that might lead some cancer patients to not appreciate equally the drugs' potential side effects and risks,' study author Dr. Gregory Abel, of the Dana-Farber Cancer Institute in Boston, said in a prepared statement. 'Oncology providers should be aware of these advertisement characteristics, as they may influence patients' perceptions of and requests for these medications.' "

Elevated WBC Count May Be Associated With Increased Cancer Risk

Lung Cancer Most Common Cancer Worldwide

Ovarian cancer rates lower in sunny areas: Modest sun exposure and vitamin D pills could lower risk, study says "The findings, say researchers, suggest that sun exposure — and, more precisely, vitamin D production in the body — help prevent this cancer."

Women and cancer - the shocking facts "A recent report on cancer among women in Ireland threw up some startling facts and figures. It revealed that around 3,500 women die as a result of the disease every year in this country. However more shocking than that is the fact that this rate is the highest in western Europe apart from Denmark."

ARTICLES:

Vitamin D Status and Cancer Incidence and Mortality: Something New Under the Sun "Sunlight generally is an effective means of generating large amounts of vitamin D, but it may not be safe for all persons. For many individuals, including those who are darkly pigmented or who live at northern latitudes, sunlight exposure may also be insufficient to generate adequate vitamin D. Conversely, vitamin D supplements are widely available, inexpensive, and believed to be safe over a large dosing range. As is often pointed out, the present recommended allowance for vitamin D—400 IU—for individuals aged 50–70 years is inadequate even to maintain skeletal health and is probably too low for meaningful anticancer effects (25)."

JOURNAL ARTICLES:

A phospholipase C-dependent intracellular Ca2+ release pathway mediates the capsaicin-induced apoptosis in HepG2 human hepatoma cells. (Arch Pharm Res. 2005)

Antioxidant vitamins and risk of lung cancer. (Curr Pharm Des. 2006) "Antioxidant vitamins were observed to have no clear protective effect, though there was some evidence pointing to a protective role for vitamins C and E. Vitamin A, in contrast, evinced no clear effect. Insofar as provitamin A carotenoids were concerned, lutein/zeaxanthin, lycopene and alpha-carotene displayed a certain protective trend, yet beta-carotene exhibited no protective effect whatsoever; and indeed, there was speculation as to whether it might even be pernicious in smokers. Beta-criptoxanthin, on the other hand, showed a more consistent protective effect."

Antioxidants vitamin C and vitamin e for the prevention and treatment of cancer. (J Gen Intern Med. 2006) "CONCLUSIONS: The systematic review of the literature does not support the hypothesis that the use of supplements of vitamin C or vitamin E in the doses tested helps prevent and/or treat cancer in the populations tested. There were isolated findings of benefit, which require confirmation."

Association Between Circulating White Blood Cell Count and Cancer Mortality (Arch Intern Med. 2006)

Cancer survival is dependent on season of diagnosis and sunlight exposure. (Int J Cancer. 2006) "We found seasonality in cancer survival to be stronger in women than in men. Our results add to a growing body of evidence that vitamin D metabolites play an important role in cancer survival."

Recreational Physical Activity and Sedentary Behavior in Relation to Ovarian Cancer Risk in a Large Cohort of US Women (American Journal of Epidemiology 2006) "Results from this study suggest that high levels of sedentary behavior may increase the risk of ovarian cancer, but they do not support a major impact of light and moderate physical activity on ovarian cancer risk."

The effect of lifestyle factors on gynaecological cancer. (Best Pract Res Clin Obstet Gynaecol. 2006)

Zinc, Copper, and Magnesium and Risks for All-Cause, Cancer, and Cardiovascular Mortality. (Epidemiology. 2006) "CONCLUSIONS:: High serum copper, low serum magnesium, and concomitance of low serum zinc with high serum copper or low serum magnesium contribute to an increased mortality risk in middle-aged men."

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