Hypertension

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Hypertension

NIH - Medical Encyclopedia: Essential hypertension

"Essential hypertension refers to high blood pressure with no identifiable cause. ...Usually, high blood pressure has no symptoms at all. That is why it is often called the 'silent killer.' "

Highlighted Article

Natural antioxidants from tomato extract reduce blood pressure in patients with grade-1 hypertension: a double-blind, placebo-controlled pilot study. (Am Heart J. 2006)

"A short-term treatment with antioxidant-rich tomato extract can reduce blood pressure in patients with grade-1 HT, naive to drug therapy."

Hypertension

General Information

NEWS:

AMA Wants Warning Labels on High-Salt Food

High resting heart rate with high normal BP risky "People who have 'prehypertension' and an elevated heart rate at rest have a greater risk of heart disease and death than comparable people with a lower resting heart rate, a new study shows. 'A heart rate above 80 beats per minute at rest is associated with increased risk of heart disease in people with high blood pressure, and, in this latest study, even in people with borderline high blood pressure,' study chief Dr. Dana E. King told Reuters Health."

Hot Weather Heats Up Blood Pressure

Salt Initiative Backed by Health Professionals

ARTICLES:

Dietary Approaches to Prevent and Treat Hypertension

High Blood Pressure: FAQs

Sodium "Limiting the amount of salt, or sodium, in your diet is important if you have high blood pressure, congestive heart failure or fluid retention that causes leg swelling (edema). Some people are genetically more likely to hold sodium in the body after eating foods with salt. Everyone with high blood pressure should reduce their salt consumption because this lowers blood pressure and allows some of the most common blood pressure medicines to work better."

JOURNAL ARTICLES:

As the New Definitions of Hypertension Take Hold, the Implications for Diagnosis, Treatment, and Disease States Make the News (Medscape Cardiology. 2006)

Association of Impaired Diurnal Blood Pressure Variation With a Subsequent Decline in Glomerular Filtration Rate (Arch Intern Med. 2006) "Background Most healthy people exhibit a decrease in systolic blood pressure (SBP) at night. A drop of less than 10% from mean daytime values (nondipping) is associated with chronic kidney disease, insulin resistance, and cardiovascular events. Whether nondipping precedes a decline in renal function remains unclear. . Conclusion Blunted diurnal blood pressure variation is associated with a subsequent deterioration in renal function that is independent of SBP load and other risk factors for renal impairment."

Asymptomatic carotid lesions and aging: role of hypertension and other traditional and emerging risk factors. (Arch Med Res. 2006) "BACKGROUND: We evaluated the prevalence of intima-media thickening (IMT) and asymptomatic carotid plaque (ACP) in a group of subjects with or without traditional and/or emerging risk factors (RF). . CONCLUSIONS: IMT and ACP of carotid arteries are significantly more frequent in patients >65 years vs. those less 65 years and in hypertensive patients in comparison to controls. Finally, we have found that the seropositivity of infection and the presence of higher levels of marker of inflammation were correlated with carotid lesion."

Birth weight and adult hypertension. (Circ J. 2006)

Development of microalbuminuria in essential hypertension. (Curr Hypertens Rep. 2006)

Effects of dietary saturated, monounsaturated, and n-3 fatty acids on blood pressure in healthy subjects (American Journal of Clinical Nutrition 2006)

[Epidemiology of hypertension.] (Dtsch Med Wochenschr. 2006)

Estrogen and hypertension. (Curr Hypertens Rep. 2006)

Evaluation and Treatment of Patients With Severely Elevated Blood Pressure in Academic Emergency Departments: A Multicenter Study (Annals of Emergency Medicine 2006)

Exaggerated Blood Pressure Response to Exercise is Associated With Inflammatory Markers. (Journal of Cardiopulmonary Rehabilitation 2006) "PURPOSE: An exaggerated blood pressure (EBP) response to exercise has been shown to be a predictor of future hypertension and risk of cardiovascular mortality. Although EBP is associated with endothelial dysfunction and increased left ventricular hypertrophy, the underlying mechanisms are not fully understood. Inflammatory markers, C-reactive protein (CRP) and white blood cells (WBCs), were predictive of future hypertension. The objective of this study was to examine the hypothesis that increasing levels of CRP and WBCs would be related to an EBP response during exercise. . CONCLUSIONS: These results suggest that inflammation may be associated with an EBP response during exercise testing."

Here Come the Baby Boomers And Their Hypertension -- But Does Hypertension Really Exist? (Medscape Cardiology. 2005)

Hypertension in Children and Adolescents (Am Fam Physician 2006)

Hypertension in older people: part 1. (J Clin Hypertens (Greenwich). 2006)

Is hypertension an inflammatory process? (Curr Pharm Des. 2006) "Recently, chronic low grade low-grade inflammation has been identified as an integral part in the pathogenesis of vascular disease. Of note, inflammation may also be implicated in the development of hypertension, either as a primary or secondary event. Indeed, several clinical studies have demonstrated increased numbers of well recognised pro-inflammatory markers, such as high sensitive C-reactive protein (hsCRP), in patients with hypertension, even after adjustment for potential confounding factors. Furthermore, elevated hsCRP levels have also been shown to be predictive for the development of hypertension in prehypertensive and normotensive patients."

Markers of inflammation are inversely related to physical activity and fitness in sedentary men with treated hypertension. (Am J Hypertens. 2006) "CONCLUSIONS: The observed inverse relations between physical fitness and hs-CRP and between level of physical activity and sE-selectin in drug-treated, hypertensive sedentary men indicates a beneficial effect of good fitness status as well as activity of low intensity on vessel wall inflammation."

Neglected nephropathy. (Aust Fam Physician. 2006) "BACKGROUND: Diabetic nephropathy is a significant contributor to the morbidity, mortality and health care cost among patients with diabetes. . DISCUSSION: Prevention and slowing progression are the most important aspects of the management of diabetic nephropathy. This involves monitoring renal function and risk factors for renal damage and early active intervention. The angiotensin converting enzyme inhibitors and receptor antagonists are important components of therapy, both for controlling hypertension and for slowing the progression of micro and macroalbuminuria."

Nitric oxide in hypertension. (J Clin Hypertens (Greenwich). 2006) "Hypertension is a major risk factor for cardiovascular disease, and reduction of elevated blood pressure significantly reduces the risk of cardiovascular events. Endothelial dysfunction, which is characterized by impairment of nitric oxide (NO) bioavailability, is an important risk factor for both hypertension and cardiovascular disease and may represent a major link between the conditions. Evidence suggests that NO plays a major role in regulating blood pressure and that impaired NO bioactivity is an important component of hypertension."

Nocturnal hypertension in mice consuming a high fructose diet. (Auton Neurosci. 2006) "OBJECTIVE: To investigate the effect of fructose consumption on the light/dark pattern of blood pressure, heart rate and autonomic neural function in mice. BACKGROUND: Insulin resistant diabetes is associated with hypertension and autonomic dysfunction. There is evidence that the increasing incidence of diabetes may be related to dietary changes, including consumption of high levels of fructose. . CONCLUSION: A high fructose diet in mice produced nocturnal hypertension and autonomic imbalance which may be related to activation of sympathetic and angiotensin systems."

Nondipping blood pressure patterns among individuals with essential hypertension: A review of the literature. (Eur J Cardiovasc Nurs. 2006) "CONCLUSION: Knowledge of the potential factors associated with an altered nighttime BP pattern is of importance because it can help identify persons at risk for nondipping BP patterns and potential target organ damage. Furthermore, knowledge of these factors associated with a nondipping BP profile will lay the foundation for interventions to prevent/treat alterations in nighttime BP patterns."

Reactivity of Ambulatory Blood Pressure to Physical Activity Varies With Time of Day (Hypertension. 2006)

Systolic hypertension in elderly patients. (Semin Cardiothorac Vasc Anesth. 2006) "In older subjects, systolic blood pressure and pulse pressure are higher, whereas diastolic blood pressure is lower than in younger subjects."

Update on hypertension and Alzheimer's disease. (Neurol Res. 2006)

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