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Menopause

General Information

NEWS:

Depression Linked to Approach of Menopause

Dry Eye Strikes Many Menopausal Women

High Homocysteine Levels Linked to Risk for Hip Fracture in Postmenopausal Women

Prior Function and Relationship, More Than Hormones, Affect Sexual Function for Midlife Women

Twins More Likely to Have Premature Menopause "A new study from Cornell University in New York shows twins are between three- and five-times more likely to have premature ovarian failure (POF) at ages 40 and 45 than the general population. POF from natural causes before the age of 40 affects about 1 percent of women."

ARTICLES:

8 Causes of Night Sweats

JOURNAL ARTICLES:

A daily intake of approximately 6 µg vitamin B-12 appears to saturate all the vitamin B-12-related variables in Danish postmenopausal women (American Journal of Clinical Nutrition, 2006) "Conclusion: A daily vitamin B-12 intake of 6 µg appeared to be sufficient to correct all the vitamin B-12-related variables measured in the postmenopausal Danish women in this study."

Age at menopause and mortality in Japan: the jichi medical school cohort study. (J Epidemiol. 2006) "CONCLUSIONS: Our data suggest that menopause aged younger than 40 years increases the risk of death from all causes among the Japanese."

Age at menopause in Latin America. (Menopause. 2006) "The median AM of women in all centers was 48.6 years, ranging from 43.8 years in Asuncion (Paraguay) to 53 years in Cartagena de Indias (Colombia)."

Cardiovascular disease after menopause: a growing epidemic. (Minerva Ginecol. 2006) "Coronary heart disease (CHD) remains the major cause of mortality in women after menopause. At the time of menopause risk factors change to increase the risk of CHD. Although hormone replacement therapy improves some of these risk factors, no overall cardiovascular benefit has been noted with this therapy. There are parallel twin epidemics occurring in postmenopausal women, one being cardiovascular disease and the other metabolic syndrome, in which there appears to be a connection. Metabolic risk factors such as elevated triglyceride levels, decreased HDL-cholesterol levels and glucose abnormalities have been suggested to portend a greater CHD risk in women than men."

Determinants of age at menopause in women attending menopause clinics in Italy. (Maturitas. 2006) "RESULTS: The mean age at spontaneous menopause was 51.2. The age at menopause did not markedly changed with cohort of birth. Higher education was associated with lower age at menopause (51.1 in women with low education versus 51.3 for women with high school or university degree, p<0.05). A higher body mass index (BMI) was associated with later age at menopause. Smokers reported a lower age at menopause (51.2 in nonsmokers versus 51.1 in smokers, p<0.05). A later age at menarche was associated with a later age at menopause. Likewise, lifelong irregular menstrual cycles and higher parity were related with later age at menopause. No association emerged between ever oral contraceptive use and age at menopause."

Differential associations for menopause and age in measures of vitamin K, osteocalcin, and bone density: a cross-sectional exploratory study in healthy volunteers. (Menopause. 2006)

[Factors related to frequency of sexual activity of postmenopausal women.] (ev Assoc Med Bras. 2006)

Fat mass rather than muscle strength is the major determinant of physical function and disability in postmenopausal women younger than 75 years of age. (Menopause. 2006) "CONCLUSIONS:: Our results support the role of fat mass as the primary risk marker for disability, which might later accelerate by the age-related decrease in lean mass and the development of sarcopenia after the age of 75 years."

Female psychopathologic profile during menopausal transition: A preliminary study. (aturitas. 2006) "CONCLUSIONS: Our preliminary data show a high correlation between a history of depressive disorder and recurrence of depression in the menopausal period. Perimenopause seems to be a higher risk period for the development of a depressive disease compared to menopausal status. The somatization cluster warrants further investigation."

[Hypertension in women after menopause.] (Presse Med. 2006)

Hypoactive sexual desire disorder in postmenopausal women. (Gynecol Endocrinol. 2006) "Hypoactive sexual desire disorder (HSDD), a persistent absence of sexual fantasies or thoughts and/or desire for and receptivity to sexual activity that causes personal distress, is experienced by some postmenopausal women. Even though conventional hormone therapy with estrogens or estrogens and progestogens may be effective for vaginal atrophy, increasing vaginal lubrication and reducing dyspareunia, it has not been shown to consistently increase sexual desire or activity and many women with sexual dysfunction remain unresponsive."

Insulin resistance in postmenopausal women with metabolic syndrome and the measurements of adiponectin, leptin, resistin, and ghrelin. (Am J Obstet Gynecol. 2006)

Lifetime changes in the vulva and vagina. (Arch Gynecol Obstet. 2006)

Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se? (Osteoporos Int. 2006)

Medial frontal cortex perfusion abnormalities as evaluated by positron emission tomography in women with climacteric symptoms. (Menopause. 2006)

Menopausal symptoms and health problems of women aged 50-65 years in southern Jordan. (Climacteric. 2006) "The most frequently reported somatic symptoms were joint aches/stiffness (89%), bone pains (74%) and paresthesia in the extremities (51%). Hot flushes were experienced by 62% and urinary incontinence by 30%. Almost 62% reported irritability and mood changes, 56% had high blood pressure, and 18% and 14% suffered from urinary tract infection and reproductive tract infection, respectively. Eight percent and 11% reported ever-screening by mammogram and cervical smear, respectively, and 11% reported performing breast self-examination regularly. Regular physical exercise was reported by 8%, and 81% were overweight or obese."

Menopause is an independent factor augmenting the age-related increase in arterial stiffness in the early postmenopausal phase. (Atherosclerosis. 2006)

Migraine and the menopause. (J Br Menopause Soc. 2006)

Relationships of age at menarche and menopause, and reproductive year with mortality from cardiovascular disease in Japanese postmenopausal women: the JACC study. (J Epidemiol. 2006) "CONCLUSIONS: The possible association between early menopause and coronary heart disease among middle-aged women was consistent with the result of observational studies for Caucasian women, and can be explained by a protective effect of endogenous estrogen on the development of atherosclerosis."

Rhinitis and snoring as risk factors for hypertension in post-menopausal women. (Respir Med. 2006)

Severe hot flashes are associated with chronic insomnia. (Arch Intern Med. 2006) "CONCLUSIONS: Severe hot flashes are strongly associated with chronic insomnia in midlife women. The presence of hot flashes should be systematically investigated in women with insomnia. Treating hot flashes could improve sleep quality and minimize the deleterious consequences of chronic insomnia."

Sexual and psychological symptoms in the climacteric years. (Maturitas. 2006) "CONCLUSION: Depressive and sexual symptoms presented greater severity in the post-menopausal group. Both clusters of symptoms were strongly associated with life events. The parallel course of the two clusters could be related with a common pathoplastic action of life events, both on sexual symptoms and on depressive symptoms, occurring right at the time that a woman has to face the transition into menopause."

Sexuality and the menopause. (J Br Menopause Soc. 2006)

Sleep disturbances, oxidative stress and cardiovascular risk parameters in postmenopausal women complaining of insomnia. (Climacteric. 2006)

The length of perimenopausal menstrual cycles increases later and to a greater degree than previously reported. (Fertil Steril. 2006)

The neurology of menopause. (Neurologist. 2006)

The prevalence and the age at the onset of menopause in Turkish women in rural area. (Saudi Med J. 2006)

The role of calcium in peri- and postmenopausal women: 2006 position statement of The North American Menopause Society. (Menopause. 2006) "CONCLUSIONS:: The most definitive role for calcium in peri- and postmenopausal women is in bone health, but, like most nutrients, calcium has beneficial effects in many body systems. Based on the available evidence, there is strong support for the importance of ensuring adequate calcium intake in all women, particularly those in peri- or postmenopause."

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