NeuroProtection
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NeuroProtection
General Information
NEWS:
Exercise May Have Neuroprotective Effect "Exercise helps maintain brain structure and function with aging and may delay onset of Alzheimer's disease and other dementias ."
How an Herb Might Help the Brain
Resveratrol-A boon for treating Alzheimer's disease? (Brain Res Brain Res Rev. 2006)
ARTICLES:
JOURNAL ARTICLES:
Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders. (Mol Nutr Food Res. 2006)
Is magnesium neuroprotective following global and focal cerebral ischaemia? A review of published studies. (Magnes Res. 2006) "Neuroprotective activity with magnesium associated with animal models of cerebral ischaemia, seizure, perinatal hypoxia/ischaemia, subarachnoid haemorrhage and traumatic brain injury has provided the justification for clinical stroke trials. However, the recent IMAGES stroke clinical trial found magnesium to be largely ineffective. … data from our own laboratory indicates that magnesium is only neuroprotective when combined with post-ischaemic hypothermia. These data provide a possible explanation of why the IMAGES trial was largely unsuccessful, as current stroke patient management does not involve hypothermia induction."
Neuroprotective and disease-modifying effects of the ketogenic diet. (Behav Pharmacol. 2006)
Neuroprotective effects of cognitive enrichment. (Ageing Res Rev. 2006) "Cognitive enrichment early in life, as indicated by level of education, complexity of work environment or nature of leisure activities, appears to protect against the development of age-associated cognitive decline and also dementia. These effects are more robust for measures of crystallized intelligence than for measures of fluid intelligence and depend on the ability of the brain to compensate for pathological changes associated with aging. This compensatory ability is referred to as cognitive reserve. The cognitive reserve hypothesis suggests that cognitive enrichment promotes utilization of available functions. Alternatively, late life cognitive changes in cognition may be linked to a factor, such as cholinergic dysfunction, that is also present early in life and contributes to the reduced levels of early life cognitive enrichment."
Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia. (Neurosci Lett. 2006 ) "These results demonstrate that quercetin, a natural flavonoid reduces global ischemia-induced neuronal damage through inhibition of MMP-9 activity."
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