Nocturia - Enuresis - Overactive Bladder

Overactive Bladder was added to this topic on June 24, 2006.

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Nocturia - Enuresis - Overactive Bladder

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Health Tip: About Overactive Bladder

Hormone Imbalance Could Spur Some Bed-Wetting: Finding may explain why some children don't respond to treatment "An imbalance in a hormone-like substance called prostaglandin could explain tough-to-treat bed-wetting in some children, Danish researchers report. Most children have their bed-wetting controlled by a medication called desmopressin, which reduces the amount of urine they produce at night. But about 30 percent of kids don't respond to the drug. … Compared with children who responded to desmopressin, the children who did not respond excreted twice as much urine during the night. In addition, the urine of children who wet their beds during the experiment contained more sodium, urea and prostaglandin than the other children, the researchers found."

Nocturnal Polyuria Linked to a Circadian Rhythm Disorder of Arginine Vasopressin

ARTICLES:

JOURNAL ARTICLES:

A population study of nocturia in Singapore. (BJU Int. 2006)

Association between primary nocturnal enuresis and habitual snoring in children. (Urology. 2006) "CONCLUSIONS: In a community sample of children, those with habitual snoring more often had primary nocturnal enuresis than did those without snoring."

Decrease in nocturnal urinary levels of arginine vasopressin in patients with nocturnal polyuria. (Urology. 2006) "CONCLUSIONS: The present data have demonstrated that the significant decrease in urinary AVP/urinary creatinine level at 6 am may contribute to the increased nocturnal voided volume followed by nocturia and that the circadian rhythm disorder of AVP can be predicted by a noninvasive test measuring urinary AVP/urinary creatinine in the urine voided early in the morning."

Differences in characteristics of nocturnal enuresis between children and adolescents: a critical appraisal from a large epidemiological study. (BJU Int. 2006) "CONCLUSIONS: The present finding suggesting that PNE spontaneously resolves with increasing age probably applies only to those with mild enuretic symptoms. There are significant differences in characteristics between younger enuretic children and older subjects. As age increases there is an increasing proportion of enuretic patients with more severe bed-wetting. Enuretic children aged >10 years and adolescents have significantly more daytime urinary symptoms and incontinence. The previously reported low prevalence of PNE in Hong Kong was probably due to parental indifference to the problem."

Epidemiologic survey of lower urinary tract symptoms in Japan. (Urology. 2006) "RESULTS: The responses from 4570 subjects (mean age 61 years) were analyzed. The prevalence rate for daytime urinary frequency of 8 and 11 times or more daily was 50% and 11%, respectively. The prevalence of nocturia occurring 1 and 3 or more times/night was 69% and 14%, respectively. For other symptom frequency (ie, weak urine flow, sensation of residual urine, bladder pain, urinary urgency, urgency incontinence, stress incontinence, and incontinence pad use), the prevalence rates ranged from 2% to 27% for 1 or more times/wk and 1% to 20% for 1 or more times/day."

[Epidemiology and pathophysiology of overactive bladder.] (Urologe A. 2006) "According to the new ICS classification overactive bladder (OAB) is defined as a complex of symptoms such as frequency, nocturia, and urgency with or without urge urinary incontinence. Urgency is the key symptom that leads to the diagnosis. The prevalence of overactive bladder in the general adult population is approximately 17%. This number increases with advancing age. Incontinence events are reported in approximately one-third of these patients."

Is nocturia equally common among men and women? A population based study in Finland. (J Urol. 2006)

Is sensory urgency part of the same spectrum of bladder dysfunction as detrusor overactivity? (Int Urogynecol J Pelvic Floor Dysfunct. 2006) "It has been suggested that the urogynecological diagnosis of sensory urgency is an early form of detrusor overactivity and may be just earlier in the spectrum of disease. The former term is generally defined as increased perceived bladder sensation during filling, a low first desire to void and low bladder capacity in the absence of recorded urinary tract infection (UTI) or detrusor overactivity. . Overall, sensory urgency and detrusor overactivity appear to be part of the same spectrum of bladder dysfunction."

Nocturia and circadian blood pressure profile in healthy elderly male volunteers. (J Urol. 2006)

Nocturia and Obesity: A Population-based Study in Finland. (Am J Epidemiol. 2006) "The authors conclude that obesity is associated with increased nocturia, more strongly among women than among men."

Nocturia in sleep-disordered breathing. (Sleep Med. 2006)

Nocturic frequency is related to severity of obstructive sleep apnea, improves with continuous positive airways treatment. (Am J Obstet Gynecol. 2006) "In patients with OSA and nocturia, nocturic frequency was related to age, diabetes, and severity of OSA . Patients with OSA and nocturia who were treated with CPAP demonstrated a significant decrease in nocturic frequency ."

Nocturnal enuresis and overactive bladder in children: an epidemiological study. (Int J Urol. 2006) "CONCLUSIONS: Overall, NE and OAB were detected in 5.9% and 17.8% of primary schoolchildren, respectively. The link between NE and OAB symptoms, urinary tract infections and constipation deserves more attention."

Nocturnal polyuria in patients with lower urinary tract symptoms and response to alpha-blocker therapy. (Urology. 2006) "CONCLUSIONS: NP is a common symptom accompanying LUTS suggestive of BPH. Our results showed that it is significantly related to the duration of LUTS and amount of water intake before sleep. NP cannot be treated with alpha-blocker therapy, although there is improvement in LUTS suggestive of BPH."

Overactive bladder in Parkinson's disease: alteration of brainstem raphe detected by transcranial sonography (European Journal of Neurology 2006) "Urinary dysfunction is very common in idiopathic Parkinson's disease (PD) and manifests primarily with symptoms of overactive bladder (OAB). Affection of central serotonergic systems has been suggested to play a role in OAB."

Perceptions and behaviours of women with bladder control problems. (Fam Pract. 2006)

Predictive factors for nocturia in elderly men: a cross-sectional study in 21 general practices. (BJU Int. 2006)

Prevalence and bother of nocturia, and causes of sleep interruption in a Danish population of men and women aged 60-80 years. (BJU Int. 2006) "The prevalence of nocturia increased with age. The overall prevalence of nocturia was 77% and there was no difference between men and women (P = 0.11), but men had slightly more severe nocturia than women. The bother caused by nocturia in men and women increased with the severity of nocturia, and women were slightly more bothered than men when the degree of nocturia was >2 voids/night. Nocturia was the most frequent self-reported reason for waking at night, followed by thirst."

Relationships among symptoms, bother, and treatment satisfaction in overactive bladder patients. (Neurourol Urodyn. 2006) "CONCLUSIONS: We conclude that the counting of episodes of OAB symptoms only insufficiently describes the afflicted patients. Patient bother is the strongest individual component but only poorly explained by episodes of the four symptoms defining OAB. Alterations of bother may better reflect patient-relevant outcomes in OAB treatment than alterations in the number of symptom episodes."

The impact of detrusor overactivity on bladder function in younger and older women. (J Urol. 2006) "CONCLUSIONS: From young adulthood to old age DO appears to affect bladder function parameters. It is associated with decreased bladder capacity and increased bladder sensation. Moreover, in younger adults DO is also associated with increased detrusor contraction strength, which is an association not seen in older individuals. This age associated loss of muscle function may be related to sarcopenia, implying that different treatments may be appropriate in older adults."

The prevalence of ADHD in children with enuresis: comparison between a tertiary and non-tertiary care sample. (Acta Paediatr. 2006) "CONCLUSION: The prevalence rate of ADHD is increased in an enuretic population compared to community samples (3-5%). Moreover, enuretic children admitted to tertiary care show significantly higher comorbidity than non-tertiary care patients. The ADHD prevalence in the former group increases with older age, suggesting therapy resistance and a negative prognosis for enuresis in the case of comorbidity."

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