Supplements - Nutrition

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Supplements - Nutrition

General Information - Vitamins and Supplements

NEWS:

Copper, magnesium, zinc levels tied to mortality

Herbals Plus Conventional Meds Can Be Dangerous Mix "The most common and dangerous combinations involved two or more nonsteroidal anti-inflammatory drugs (NSAIDS), or NSAIDS and the herb ginkgo. Other dangerous combinations included over-the-counter pain relievers such as ibuprofen and calcium supplements with prescribed medication."

Iron, Folate Supplements May Harm Kids in Regions Rife With Malaria

NIH panel urges more informed approach to multivitamin/mineral use for chronic disease prevention

Supplement setbacks: Alternative remedies fail government tests but should consumers care?

The vitamins we all need — some even more than others

ARTICLES:

JOURNAL ARTICLES:

A randomized, double-blind, placebo-controlled trial of nutritional supplementation during acute illness. (Am J Med. 2006) "PURPOSE: The study tested whether nutritional support of older patients during acute illness leads to a clinical benefit. … CONCLUSION: Oral nutritional supplementation of acutely ill patients improved nutritional status and led to a statistically significant reduction in the number of non-elective readmissions."

Antioxidant vitamins and minerals in prevention of cancers: lessons from the SU.VI.MAX study. (Br J Nutr. 2006) "Antioxidant supplementation may have a beneficial effect upon cancer incidence only in healthy subjects who are not exposed to cancer risk and who have a particularly low baseline status. High doses of antioxidant supplementation may be deleterious in subjects in whom the initial phase of cancer development has already started, and they could be ineffective in well-nourished subjects with adequate antioxidant status."

Factors associated with dietary supplement use among prescription medication users. (Arch Intern Med. 2006) "CONCLUSION: One in 4 prescription medication users took an NVDS in the prior 12 months, yet the majority did not share this with a conventional medical professional."

Multivitamin/Mineral Supplements and Prevention of Chronic Disease

National Institutes of Health State-of-the-Science Conference Statement: Multivitamin/Mineral Supplements and Chronic Disease Prevention (Annals 2006) "It appears that use is higher among women and among the children of women who use supplements; in elderly persons; among people with more education, higher income, healthier lifestyles and diets, and lower body mass indices; and among residents of the western United States. Individuals with chronic illnesses or who are seeking to prevent recurrence of a serious disease (for example, cancer) also tend to be more frequent users. Many dietary supplement users perceive their health as better. Conversely, MVM use is lower among smokers and certain ethnic and racial groups, such as African-American persons, Hispanic persons, and Native Americans, while certain Asian ethnic groups appear to have higher MVM use. Ironically, populations at highest risk for nutritional inadequacy who might benefit the most from MVM are the least likely to use such products. …"

[Vitamins and minerals in food supplements Up-to-date risk assessment.] (Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2006)

The Efficacy and Safety of Multivitamin and Mineral Supplement Use To Prevent Cancer and Chronic Disease in Adults: A Systematic Review for a National Institutes of Health State-of-the-Science Conference. (Ann Intern Med. 2006) "BACKGROUND: Multivitamin and mineral supplements are the most commonly used dietary supplements in the United States. PURPOSE: To synthesize studies on the efficacy and safety of multivitamin/mineral supplement use in primary prevention of cancer and chronic disease in the general population. … In a poorly nourished Chinese population, combined supplementation with beta-carotene, alpha-tocopherol, and selenium reduced the incidence of and mortality rate from gastric cancer and the overall mortality rate from cancer by 13% to 21%. In a French trial, combined supplementation with vitamin C, vitamin E, beta-carotene, selenium, and zinc reduced the rate of cancer by 31% in men but not in women. Multivitamin and mineral supplements had no significant effect on cardiovascular disease or cataracts, except that combined beta-carotene, selenium, alpha-tocopherol, retinol, and zinc supplementation reduced the mortality rate from stroke by 29% in the Linxian study and that a combination of 7 vitamins and minerals stabilized visual acuity loss in a small trial. Combined zinc and antioxidants slowed the progression of advanced age-related macular degeneration in high-risk persons. No consistent adverse effects of multivitamin and mineral supplements were evident. … Findings may not apply to use of commercial multivitamin supplements by the general U.S. population. CONCLUSIONS: Evidence is insufficient to support the presence or absence of benefits from use of multivitamin and mineral supplements to prevent cancer and chronic disease."

[The SU.VI.MAX study, a randomized, placebo-controlled trial on the effects of antioxidant vitamins and minerals on health.] (Ann Pharm Fr. 2006)

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