Gastroesophageal Reflux Disease

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Gastroesophageal Reflux Disease

Risk Factors

NEWS:

Large waist linked to acid reflux in whites

ARTICLES:

JOURNAL ARTICLES:

Correlation of endoscopic severity of gastroesophageal reflux disease (gerd) with body mass index (bmi). (J Coll Physicians Surg Pak. 2007) "Conclusion: Higher BMI seems to be associated with higher degree of endoscopic GERD severity."

Gastroesophageal reflux disease and obesity. Pathophysiology and implications for treatment. (J Gastrointest Surg. 2007) "These data showed that: (a) BMI was independently associated to the severity of GERD; and (b) in most morbidly obese patients with GERD, reflux occurred despite normal or hypertensive esophageal motility. These findings show that the pathophysiology of GERD in morbidly obese patients might differ from that of nonobese patients, suggesting the need for a different therapeutic approach."

Lifestyle factors and risk for symptomatic gastroesophageal reflux in monozygotic twins. (Gastroenterology. 2007) "Conclusions: BMI, tobacco smoking, and physical activity at work appear to be risk factors for frequent GER symptoms, whereas recreational physical activity appears to be beneficial. Association between BMI and frequent GER symptoms among men seems to be attenuated by genetic factors."

Prevalence of overweightedness in patients with gastro-esophageal reflux. (World J Gastroenterol. 2007)

The Effects of Dietary Fat and Calorie Density on Esophageal Acid Exposure and Reflux Symptoms. (Clin Gastroenterol Hepatol. 2007) "CONCLUSIONS: Calorie density determines the severity of esophageal acid exposure in gastroesophageal reflux disease after a meal; however, the percentage fat content of the diet has important effects on the frequency of reflux symptoms."

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