Autism and Asperger

• Diagnosis, Imaging, Screening
• General Information
• Guidelines
• Internet Sites
• Risk Factors
• Risk Reduction
• Treatment - Daily Report

REVIEW our Selected Autism - Asperger Articles in 2006. Stay informed and updated!

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Autism and Asperger

NIH - Medical Encyclopedia Autism

"Most parents of autistic children suspect that something is wrong by the time the child is 18 months old and seek help by the time the child is 2. Children with autism typically have difficulties in verbal and nonverbal communication, social interactions, and pretend play. In some, aggression -- toward others or self -- may be present. Some children with autism appear normal before age 1 or 2 and then suddenly "regress" and lose language or social skills they had previously gained. This is called the regressive type of autism. People with autism may perform repeated body movements, show unusual attachments to objects or have unusual distress when routines are changed. Individuals may also experience sensitivities in the senses …"

NIH - Medical Encyclopedia Asperger syndrome

"The child with Asperger shows below-average nonverbal communication gestures, fails to develop peer relationships, has an inability to express pleasure in other people's happiness, and lacks the ability to reciprocate emotionally in normal social interactions. The condition appears to be more common in boys than in girls. There are likely genetic factors, but some theories suggest a prenatal infection may be to blame. While people with Asperger syndrome are frequently socially inept, many have above-average intelligence, and they may excel in fields like computer programming and science. There is no delay in cognitive development, in the development of age-appropriate self-help skills, or in curiosity about the environment. Generally, there is no language development delay."

Highlighted Articles

A Prospective Study of Response to Name in Infants at Risk for Autism (Arch Pediatr Adolesc Med 2007)

"Conclusions Failure to respond to name by age 12 months is highly suggestive of developmental abnormality but does not identify all children at risk for developmental problems. Lack of responding to name is not universal among infants later diagnosed with ASD and/or other developmental delays. Poor response to name may be a trait of the broader autism phenotype in infancy."

Structure of the Autism Symptom Phenotype: A Proposed Multidimensional Model. (Journal of the American Academy of Child & Adolescent Psychiatry. 2007)

"Conclusions: The pervasive developmental disorder symptom phenotype is composed of three domains or factors: social-communication, inflexible language and behavior, and repetitive sensory and motor behavior. Each child with pervasive developmental disorder can be characterized by these dimensions, which give an informative picture of the clinical presentation and a quantitative estimate of the severity of the disability."

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Autism and Asperger

Daily Treatment Report

Cognitive Therapy-CBT-Psychotherapy

A review of behavioral treatments for self-injurious behaviors of persons with autism spectrum disorders. (Behav Modif. 2008)

Device Therapy

Drug Side-Effects and Interactions

Risperidone-induced enuresis in two children with autistic disorder. (J Child Adolesc Psychopharmacol. 2007)

Drugs

Positive Effects of Methylphenidate on Inattention and Hyperactivity in Pervasive Developmental Disorders: An Analysis of Secondary Measures (Biological Psychiatry 2007)

Risperidone for autism spectrum disorder. (Cochrane Database Syst Rev. 2007) "AUTHORS' CONCLUSIONS: Risperidone can be beneficial in some features of autism. However there are limited data available from studies with small sample sizes. In addition, there lacks a single standardised outcome measure allowing adequate comparison of studies, and long-term followup is also lacking. Further research is necessary to determine the efficacy pf risperidone in clinical practice."

Exercise

General Information

Management of Children With Autism Spectrum Disorders. (AAP 2007)

Scientifically unsupported therapies in the treatment of young children with autism spectrum disorders. (Pediatr Ann. 2007)

As Autism Diagnoses Grow, So Do Number Of Fad Treatments, Researchers Say "Ineffective or even dangerous fad treatments for autism, always a problem, seem to be growing more pervasive, according to researchers who studied the problem."

Do behavioural approaches teach children with autism to play or are they pretending? (Autism. 2007)

Medication use among children with autism spectrum disorders. (J Child Adolesc Psychopharmacol. 2007)

Outcome for Children with Autism who Began Intensive Behavioral Treatment Between Ages 4 and 7: A Comparison Controlled Study. (Behav Modif. 2007) "Results suggest that behavioral treatment was effective for children with autism in the study."

[Frankfurt group social communication and interaction skillstraining for children and adolescents with autism spectrum disorders.] ( Kinder Jugendpsychiatr Psychother. 2007 )

Drug therapy for attention-deficit/hyperactivity disorder-like symptoms in autistic disorder. ( Paediatr Child Health. 2007) "Problems of inattention and hyperactivity affect one half of individuals with autistic disorder. … Substantial benefit in reducing inattention and hyperactivity is seen with atypical antipsychotics such as risperidone and quetiapine, although weight gain and sedation are common side effects. Moderate benefit is derived from methylphenidate, atomoxetine, some anticonvulsant medications, guanfacine and donepezil. Data show dexamphetamine, clonidine, clomipramine, mirtazapine, and fluoxetine are of unlikely benefit."

Guidelines

Internet Sites

Treatment Information

DrugBank (drug structure)

FDA - MedWatch (Drug Alerts)

Drug-Food-Supplement Information

Drug Information Online

Drug Interaction Checker

DrugDigest (drug interactions)

FDA - Drug Interactions: What You Should Know

NIH - Botanical Dietary Supplements: Background Information

NIH - Drug, Supplements, and Herbal Information

NIH - Herbal Supplements: Consider Safety, Too

NIH - Medicines

NIH - Vitamin and Mineral Supplement Fact Sheets

Nutrition

Other

Other Treatments

Effect of long-term interactive music therapy on behavior profile and musical skills in young adults with severe autism. (J Altern Complement Med. 2007)

Experimental

Scientists Reverse Symptoms of Autism in Mice "Scientists may have uncovered a way to reverse symptoms of mental retardation and autism in mice. Researchers from the Picower Institute for Learning and Memory at Massachusetts Institute of Technology (MIT) genetically manipulated the mice to model Fragile X Syndrome (FXS), which is the leading inherited cause of mental retardation and the most common genetic cause of autism. FXS is tied to a mutated X chromosome gene called the fragile X mental retardation 1 (FMR1) gene. When this gene is mutated, it can cause mild learning disabilities to severe autism. "

Supplements-Vitamins-CAM

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