Frontotemporal Dementia - Pick's Disease

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Frontotemporal Dementia - Pick's Disease

General Information

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JOURNAL ARTICLES:

Activities of daily living in frontotemporal dementia and Alzheimer disease (NEUROLOGY 2007) "Conclusion: Frontotemporal dementia has a devastating effect on activities of daily living, which is of considerable importance to caregivers and not captured by bedside cognitive tests."

Disparate letter and semantic category fluency deficits in autopsy-confirmed frontotemporal dementia and Alzheimer's disease. (Neuropsychology. 2007)

Dysphagia in Patients With Frontotemporal Lobar Dementia (Arch Neurol. 2007) "Conclusions When assessed via instrumentation, swallowing abnormalities are found in many patients with FTLD. The appearance of dysphagia signals progression of FTLD to brainstem systems."

Emotional reactivity and emotion recognition in frontotemporal lobar degeneration (NEUROLOGY 2007) "Conclusions: The socioemotional decline typically seen in frontotemporal lobar degeneration patients may result more from an inability to process certain emotions in other people than from deficits in emotional reactivity."

Frontotemporal dementia. (Semin Neurol. 2007) "Frontotemporal dementia (FTD) is an uncommon but important form of degenerative disease. It may make up 50% of dementia cases presenting before age 60. The symptoms are related to the anatomic areas affected. Neary divided the clinical syndromes into "frontotemporal dementia," "progressive nonfluent aphasia," and "semantic dementia." However, the pathology may extend beyond the frontal and temporal lobes and additional symptoms may be found. Although most cases are sporadic, some cases are genetic."

[Frontotemporal dementia.] (Presse Med. 2007) "Frontotemporal dementia usually begins before the age of 65 years. It is manifested by behavioral and language disorders. The lesions observed in frontotemporal dementia affect the frontal and temporal lobes bilaterally. One third of patients have a psychiatric diagnosis at the onset of disease. The genetic component is important: 30-50% of patients have a family history of this disease."

Frontotemporal dementia: recommendations for therapeutic studies, designs, and approaches. (Can J Neurol Sci. 2007)

Frontotemporal dementias: A review. (Ann Gen Psychiatry. 2007) "Frontotemporal dementia (FTD) is the term now preferred over Picks disease to describe the spectrum of non-Alzheimers dementias characterized by focal atrophy of the frontal and anterior temporal regions of the brain. The prevalence of FTD is considerable, though specific figures vary among different studies. It occurs usually in an age range of 35-75 and it is more common in individuals with a positive family history of dementia. The risk factors associated with this disorder include head injury and family history of FTD."

Frontotemporal dementia to Alzheimer's disease. (Dialogues Clin Neurosci. 2007)

Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder. (Arch Gen Psychiatry. 2007)

Patterns of neuropsychological impairment in frontotemporal dementia (NEUROLOGY 2007) " Conclusion: Patients with differing frontotemporal dementia phenotypes can be distinguished from each other and from Alzheimer disease using neuropsychological tests."

Pure word deafness and pure anarthria in a patient with frontotemporal dementia (European Journal of Neurology 2007)

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