Depression

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Depression

NIH - Medical Encyclopedia Depression

"Depression may be described as feeling sad, blue, unhappy, miserable, or down in the dumps. Most of us feel this way at one time or another for short periods. But true clinical depression is a mood disorder in which feelings of sadness, loss, anger, or frustration interfere with everyday life for an extended time. … The main types of depression include: Major depression -- five or more symptoms listed above must be present for at least 2 weeks, but major depression tends to continue for at least 6 months. (Depression is classified as minor depression if less than five depressive symptoms are present for at least 2 weeks.) and Dysthymia -- a chronic, generally milder form of depression but lasts longer -- usually as long as two years. Depression also includes atypical depression, postpartum depression, Premenstrual dysphoric disorder (PMDD), and Seasonal affective disorder (SAD). … If you are depressed for 2 weeks or longer, you should contact your doctor, who can offer treatment options. … Call 911, a suicide hotline, or get safely to a nearby emergency room if you have thoughts of suicide, a suicidal plan, or thoughts of harming yourself or others."

Highlighted Article

Regular exercise, anxiety, depression and personality: A population-based study. (Prev Med. 2006)

"This study corroborates and extends previous findings: regular exercise is cross-sectionally associated with lower neuroticism, anxiety and depression and higher extraversion and sensation seeking in the population."

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Depression

General Information

NEWS:

Depression Linked to Bone Loss in Younger Women "The bone loss was most pronounced in certain regions of the hip, which is troubling given that hip fractures are one of the most serious -- and potentially fatal -- consequences of osteoporosis."

Depression tied to low folate levels "Results of a new study confirm an association between folate levels and depression. The study, a pooled look at various studies on the topic, showed that people with lower levels of the B vitamin had an increased risk of depression. Whether their low folate status caused the depression, however, is unknown. "

ARTICLES:

Depression in Children

Folate and depression-a neglected problem.

Onset of confusion in the context of late-life depression.

SAD? Help for the Winter Blues

JOURNAL ARTICLES:

A meta-analysis on depression and subsequent cancer risk. (Clin Pract Epidemol Ment Health. 2007) "CONCLUSIONS: This review suggests a tendency towards a small and marginally significant association between depression and subsequent overall cancer risk and towards a stronger increase of breast cancer risk emerging many years after a previous depression."

Caffeine Consumption, Sleep, and Affect in the Natural Environments of Depressed Youth and Healthy Controls. (J Pediatr Psychol. 2007)

Comorbid alcohol and substance abuse dependence in depression: impact on the outcome of antidepressant treatment. (Psychiatr Clin North Am. 2007)

Cytomegalovirus is associated with depression and anxiety in older adults. (Brain Behav Immun. 2007)

Depression and anxiety during pregnancy: A risk factor for obstetric, fetal and neonatal outcome? A critical review of the literature. (J Matern Fetal Neonatal Med. 2007) "Results. Elevated levels of depression and anxiety were found to be associated with obstetric outcome (obstetric complications, pregnancy symptoms, preterm labor and pain relief under labor), and had implications for fetal and neonatal well-being and behavior. However, prediction of the impact of mood and anxiety disorders during pregnancy is very limited due to methodological problems."

Effect of age at onset on the course of major depressive disorder. (Am J Psychiatry. 2007)

High {omega}-6 and Low {omega}-3 Fatty Acids are Associated With Depressive Symptoms and Neuroticism. (Psychosom Med. 2007)

[Immunological aspects of depressive disorders.] (Nervenarzt. 2007)

Inflammation, Depression and Dementia: Are they Connected? (Neurochem Res. 2007) "Thus increased neurodegeneration, reduced neuroprotection and neuronal repair are common pathological features of major depression and dementia. Such changes may help to explain why major depression is a frequent prelude to dementia in later life."

Monthly variation in prevalence rates of comorbid depression and anxiety in the general population at 63-65 degrees North: The HUNT study. (J Affect Disord. 2007)

Neurobiology of depression: an integrated view of key findings. (Int J Clin Pract. 2007)

Predicting recovery from episodes of major depression. (J Affect Disord. 2007)

Relation between depressive symptoms and common carotid artery atherosclerosis in american persons >/=65 years of age. (Am J Cardiol. 2007) "In conclusion, these data indicate that depressive symptoms are associated with the development of atherosclerosis in subjects aged >/=65 years."

Self medication with St. John's wort in depressive disorders: An observational study in community pharmacies. (J Affect Disord. 2007)

Social anxiety and insomnia: the mediating role of depressive symptoms. (Depress Anxiety. 2007) "Our data support the contention that social anxiety is associated with insomnia and suggest that depression may play a vital role in this co-occurrence."

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