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Migraine and Headache

General Information

NEWS:

A Hidden Cause of Headache Pain

Increased C-reactive protein in young adult patients with migraine (Cephalalgia 2007) "This finding supports the role of inflammation in migraine, but needs confirmation in larger controlled studies."

Many Women Suffer From Midcycle Migraines "New clinical research shows that midcycle migraines are common and have a severity and duration similar to headaches occurring during the menstrual period. Midcycle migraine headaches achieve their pain intensity during 3 distinct midcycle time intervals, the authors say."

Mid-life headaches may be sign of retinal disease"Migraine and other headaches are associated with abnormalities in the small blood vessels around the retina (retinopathy) in middle-age men and women, according to data from the Atherosclerosis Risk in Communities Study."

Migraine brains may be starved of oxygen "They say their finding may help to explain why migraine sufferers have a higher risk of stroke."

Migraine linked to heart disease

Migraine Sufferers May Have Greater Risk of Retinopathy "The study concluded that people with a history of headaches were 1.3 to 1.5 times more likely to have retinopathy than individuals without a history of headaches."

Migraine Tied to Thickening in Brain Area "And changes in the brain induced by repetitive migraine attacks may make sufferers more prone to suffering from other pain disorders, the researchers theorized. This would explain the high number of people with migraine who also suffer from such conditions as fibromyalgia and back pain."

Migraine With Aura Increases Suicide Risk in Adolescents "Young adolescents with chronic daily headache (CDH), particularly those who have migraines with aura, are at 6 times greater risk for suicide than their headache-free peers, new research suggests."

Migraine With Aura Linked to Hemorrhagic Stroke in Women "New analysis of data from the Women's Health Study (WHS) shows an association between migraine with aura and hemorrhagic stroke risk in women. Migraine, particularly with aura, is well established as a risk factor for ischemic stroke as well as coronary heart disease, but the relationship with hemorrhagic stroke has been less investigated."

Migraines Change the Brain "Dr. Hadjikhani notes people with migraine are more likely to suffer from other sensitivity conditions as well, such as jaw pain, back pain, and sensitive skin. This discovery could help explain why those conditions are so common in people with these debilitating headaches."

Restless legs may be associated with migraine

Study observes increased risk for CV events in men with migraines "Data from the study, which began in 1982, demonstrated that men who reported migraines had a 24% increased risk of all CV events. The increased risk was driven largely by a 42% increase in the risk of myocardial infarction."

ARTICLES:

Men and Headaches

Tips for Avoiding Migraine Triggers

JOURNAL ARTICLES:

24-Hour Distribution of Migraine Attacks (Headache: The Journal of Head and Face Pain 2007) "Conclusion.—The main finding in our study is that migraine attacks tend to recur in a harmonic 24-hour cyclic manner with a peak around the middle of the day and that there is no difference between migraine with aura and migraine without aura regarding this."

A Retrospective, Comparative Study on the Frequency of Abuse in Migraine and Chronic Daily Headache (Headache: The Journal of Head and Face Pain 2007) "Conclusion.—The relative frequency of abuse is higher in CDH sufferers than migraineurs, suggesting that physical and sexual abuse may be risk factors for chronification."

Altered metabolism in frontal brain circuits in cluster headache (Cephalalgia 2007)

Chronic cluster headache: a French clinical descriptive study. (J Neurol Neurosurg Psychiatry. 2007) "DISCUSSION: This study confirms the existence of auras and inter-ictal signs and symptoms in patients with chronic CH, and male sex and smoking as CH risk factors. Primary and secondary chronic CH appears equally prevalent. Male sex does not appear to favour the shift to chronic CH."

Clinical description and treatment of cluster headache (Sang Thrombose Vaisseaux 2007)

Cluster headache: a review of online resources for patients and clinicians. (Curr Pain Headache Rep. 2007) "Conclusions The results of our communitywide study demonstrate the poor long-term prognosis of patients surviving hospitalization for decompensated HF. Despite advances in the therapeutic management of these patients, their long-term survival remains guarded."

Comorbidity of Migraine and Psychiatric Disorders-A National Population-Based Study. (Headache. 2007) "Conclusion.- Migraine is associated with major depressive disorder, bipolar disorder, panic disorder, and social phobia. Migraine in association with various mental health disorders results in poorer health-related outcomes compared with migraine or a psychiatric condition alone."

Depression and anxiety: effect on the migraine-obesity relationship. (Headache. 2007) "Conclusion.-Depression and anxiety were common in obese migraineurs. The relationship of obesity with migraine frequency and migraine-related disability is modified by depression and by anxiety, with the strongest effect observed in migraineurs with both depression and anxiety."

Endometriosis is associated with prevalence of comorbid conditions in migraine. (Headache. 2007) "Conclusion.-Prevalence of EM is higher in women with migraine than in nonheadache controls. Migraineurs with EM have more frequent and disabling headaches, and are more likely to have other comorbid conditions affecting mood and pain, compared to migraineurs without EM."

High prevalence of somatic symptoms and depression in women with disabling chronic headache (NEUROLOGY 2007) " Conclusions: High somatic symptom severity is prevalent in women with chronic and severely disabling headaches. Synergistic relationship to major depression exists for high somatic symptom severity, chronic headache, and disabling headache, suggesting a psychobiological underpinning of these associations."

History of childhood maltreatment is associated with comorbid depression in women with migraine (NEUROLOGY 2007) "Conclusions: Childhood maltreatment was more common in women with migraine and concomitant major depression than in those with migraine alone. The association of childhood sexual abuse with migraine and depression is amplified if abuse also occurs at a later age."

Is Headache Related to Asthma, Hay Fever, and Chronic Bronchitis? The Head-HUNT Study. (Headache. 2007) "Conclusions.-This large questionnaire-based study confirms that migraine and other headaches are associated with respiratory and allergic disorders. The magnitude of the association between headache and asthma, hay fever, and chronic bronchitis tended to be in the same order. Headache frequency seems to have a greater impact on the association with respiratory or allergic conditions than headache diagnoses. Whether it is a causal relationship is uncertain, but the results underline the importance of considering comorbid disorders among patients with frequent headache."

Is the cerebral cortex hyperexcitable or hyperresponsive in migraine? (Cephalalgia. 2007)

Migraine and depression. (Neurol Sci. 2007)

Migraine and ischaemic heart disease and stroke: potential mechanisms and treatment implications. (Cephalalgia. 2007)

Migraine and Risk of Cardiovascular Disease in Men (Arch Intern Med. 2007) "Conclusion In this large prospective cohort of apparently healthy men, migraine was associated with increased risk of major CVD, which was driven by increased risk of myocardial infarction."

Migraine aura. (Neurologist. 2007) "At present, the International Headache Society has recognized 3 "typical" auras: visual, sensory, and language. Increasing evidence from investigations in human subjects suggests that typical auras may be the clinical manifestation of a cortical spreading depression (CSD)-like phenomenon. Other studies have shown altered reactivity and processing within the cortices of migraineurs who experience an aura, which might render them more vulnerable to CSD-like events."

Migraine comorbidity constellations. (Headache. 2007)

Migraine is associated with enhanced arterial stiffness. (Hypertens Res. 2007)

Migraine with aura is a risk factor for cardiovascular and cerebrovascular disease: a critically appraised topic. (Neurologist. 2007) "CONCLUSION:: In women, active migraine with aura increases the risk of major CVD and ischemic stroke by approximately 2-fold compared with women without migraine. Active migraine without aura was not a risk factor for major CVD and stroke outcomes in this study."

Migraine without aura: comparison with cervicogenic headache. Vågå study of headache epidemiology. (Acta Neurol Scand. 2007)

Outcomes and predictors of chronic daily headache in adolescents (NEUROLOGY 2007) "Conclusions: Most adolescents with chronic daily headache (CDH) continued to have frequent headaches, although the incidence of CDH declined at follow-up. Migraine diagnosis gained prominence as headache frequency decreased. The percentages of chronic migraine in adolescents with CDH increased obviously if the appendix criteria were applied."

Post-Traumatic Stress Disorder in Episodic and Chronic Migraine. (Headache. 2007)

Probable Migraine With Visual Aura and Risk of Ischemic Stroke. The Stroke Prevention in Young Women Study. (Stroke. 2007) "CONCLUSIONS: PMVA was associated with an increased risk of stroke, particularly among women without other medical conditions associated with stroke. Behavioral risk factors, specifically smoking and oral contraceptive use, markedly increased the risk of PMVA, as did recent onset of PMVA."

Psychiatric comorbidity and suicide risk in adolescents with chronic daily headache. (Neurology. 2007) "CONCLUSIONS: This community-based study showed high comorbidity of psychiatric disorders and suicidal risk in adolescents with chronic daily headache. The presence of migraine attacks, especially migraine with aura, was the major predictor for these associations."

Recognition and Treatment of Menstrual Migraine. (Neurologist. 2007) "REVIEW SUMMARY:: Characteristics of menstrual migraine, which include functional disability, increased headache severity, and lack of aura, are often overlooked, and therefore menstrual migraine is often underdiagnosed. Use of a 3-month diary to record migraine patterns can reveal the predictable patterns associated with menstrual migraine, and a diary is demonstrated to be a useful tool in diagnosis. Optimal treatment of menstrual migraine takes advantage of the predictability of the disorder. Treatment alternatives for menstrual migraine include acute therapy and short- or long-term preventive therapies. Acute therapy is given shortly after the migraine begins. Short-term preventive therapies are effective when administered during the time that menstrual migraine is most likely to occur; the treatment window is typically 2 days prior up to 3 days after the onset of menstruation."

Recurrent primary thunderclap headache and benign CNS angiopathy (NEUROLOGY 2006)

Refractory chronic headache associated with obstructive sleep apnoea syndrome. (Cephalalgia. 2007) "Multivariate regression analysis revealed that age, male gender and body mass index were associated with OSAs. C-PAP treatment improved both sleep apnoea and headache in only a third of the cases. Patients suffering from chronic refractory headache associated with sleep or snoring, in particular those who are also middle-aged, overweight men, should be considered for polysomnography. C-PAP treatment alone does not seem to improve headache, but further investigation is needed."

Relationship Between Migraine and Patent Foramen Ovale: A Study of 121 Patients with Migraine (Headache: The Journal of Head and Face Pain 2007) "Conclusions.—Our findings suggest possible association of migraine with aura and PFO. It seems that PFO does not influence the type of aura and frequency of attacks of migraine as well as it is not associated with familial occurrence of migraine."

Similarities and Differences Between Chronic Migraine and Episodic Migraine (Headache: The Journal of Head and Face Pain 2007)

The cerebellum and migraine. (Headache. 2007)

The coexistence of anxiety and depressive personality traits in migraine. (Singapore Med J. 2007) "Results: The migraine patients showed a higher MMPI score on the following personality traits: depression (39 versus 15, p-value is less than 0.0005), and anxiety (24 versus 11, p-value equals 0.011). Both depressive and anxiety personality traits were significantly higher in migraine patients. Conclusion: All migraine patients should probably be screened for their personality traits and psychopathology using the MMPI."

The triggers or precipitants of the acute migraine attack. (Cephalalgia. 2007) "The trigger frequencies were stress (79.7%), hormones in women (65.1%), not eating (57.3%), weather (53.2%), sleep disturbance (49.8%), perfume or odour (43.7%), neck pain (38.4%), light(s) (38.1%), alcohol (37.8%), smoke (35.7%), sleeping late (32.0%), heat (30.3%), food (26.9%), exercise (22.1%) and sexual activity (5.2%). Triggers were more likely to be associated with a more florid acute migraine attack. Differences were seen between women and men, aura and no aura, episodic and chronic migraine, and between migraine and probable migraine."

Work stress and new-onset migraine in a female employee population. (Cephalalgia. 2007)

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