Brain Injury

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Brain Injury

General Information

NEWS:

After brain injury, a silent struggle to start over

After initial brain injury, damage continues

Brain-injured War Veterans Show A Faster Decline In Cognitive Functioning As They Age “A study of Vietnam war veterans who suffered brain injuries during the conflict has found that the men show a faster decline in their cognitive functioning as they grow older than veterans without such injuries.”

Doctors 'Awaken' Man 6 Years After Severe Brain Injury "The patient who is the subject of the new study underwent a 10-hour operation during which electrodes were implanted into his brain and used to stimulate the thalamus on both sides of the brain. The procedure has been used before in Parkinson's disease, dystonia, obsessive-compulsive disorder and depression."

Even Mild TBI Significantly Increases Epilepsy Risk in Children and Young Adults "A large population-based study shows even mild head injury in children and young adults significantly increases epilepsy risk up to 10 years following the initial accident and possibly beyond."

More Americans have serious head injuries "Traumatic brain injury occurs when the head suddenly and violently hits an object or when something pierces the skull and enters the brain. It can cause a range of symptoms from dizziness to coma and can be fatal."

ARTICLES:

Heads Up: Brain Injury in Your Practice A Tool Kit for Physicians

JOURNAL ARTICLES:

Abnormalities of pituitary function after traumatic brain injury in children. (J Neurotrauma. 2007) "The degree of pituitary dysfunction was independent from the severity of TBI. Our study confirms the high risk for hypopituitarism in children with TBI despite the lack of obvious clinical symptoms. We suggest screening of pituitary function after any kind of brain trauma requiring hospitalization in childhood."

Cerebellar Atrophy after Moderate-to-Severe Pediatric Traumatic Brain Injury (American Journal of Neuroradiology 2007) "CONCLUSION: Our finding of reduced cerebellar WM volume in children with TBI is consistent with evidence from experimental studies suggesting that the cerebellum and its related projection areas are highly vulnerable to fiber degeneration following traumatic insult."

Circadian rhythm sleep disorders following mild traumatic brain injury (NEUROLOGY 2007) "Conclusions: Minor traumatic brain injury might contribute to the emergence of circadian rhythm sleep disorders. Two types of these disorders were observed: delayed sleep phase syndrome and irregular sleep–wake pattern. The types differed in the subjective questionnaire scores and had distinct profiles of melatonin and temperature circadian rhythms."

Early prediction of favorable recovery six-months after mild traumatic brain injury. (J Neurol Neurosurg Psychiatry. 2007) "RESULTS: At follow-up, 64% of the 201 participating patients reported full recovery. Based on our prediction rules, patients without pre-morbid physical problems, low levels of PCS and post traumatic stress early after injury, had 90% chance to remain free of PCS. Patients with over 11 years of education, without nausea or vomiting on admission, with no additional extracranial injuries, and only low levels of pain early after injury, had 90% chance on full RTW."

Hippocampus, amygdala, and basal ganglia morphometrics in children after moderate-to-severe traumatic brain injury. (Dev Med Child Neurol. 2007) "Analysis revealed significant volume loss in the hippocampus, amydala, and globus pallidus of the TBI group."

Incidence and Outcome of Traumatic Brain Injury in an Urban Area in Western Europe over 10 Years. (Eur Surg Res. 2007)

Long-term morbidities following self-reported mild traumatic brain injury. (J Clin Exp Neuropsychol. 2007)

Mild traumatic brain injury does not predict acute postconcussion syndrome. (J Neurol Neurosurg Psychiatry. 2007) "CONCLUSIONS: There is a high rate of acute PCS in both mTBI and non-brain injured trauma patients. PCS was not found to be specific to mTBI. The use of the term PCS may be misleading as it incorrectly suggests that the basis of PCS is a brain injury."

Neurodevelopmental Consequences of Early Traumatic Brain Injury in 3-Year-Old Children (PEDIATRICS 2007) "CONCLUSIONS. Prolonged gestation is a risk factor for early epilepsy; the added increase in risk for instrument-assisted and cesarean deliveries could be attributable to factors that are related to both birth complications and epilepsy."

Neuropsychological function 23 years after mild traumatic brain injury: A comparison of outcome after paediatric and adult head injuries (Brain Injury 2007) "Conclusions: The findings indicate that children sustaining complicated mild TBI may be more vulnerable to development of chronic mild neuropsychological dysfunction than adults sustaining similar head injuries."

New onset obsessive-compulsive symptoms in children and adolescents with severe traumatic brain injury. (Depress Anxiety. 2007)

Patterns and Predictors of Swallowing Resolution Following Adult Traumatic Brain Injury. (J Head Trauma Rehabil. 2007)

Pituitary functions in the acute phase of traumatic brain injury: Are they related to severity of the injury or mortality? (Brain Injury 2007) "Conclusions: Present data clearly demonstrate that pituitary function is disturbed in TBI and the most frequently deficient pituitary hormones were gonadotrophins in the early acute phase of TBI. Basal hormone levels including cortisol, prolactin and total testosterone were related to the severity of the trauma. However there was no relation between basal hormones and mortality due to TBI. Age and GCS were significantly related to mortality."

Postnatal lead poisoning impairs behavioral recovery following brain damage. (Neurotoxicology. 2007)

Prognostic Value of Cause of Injury in Traumatic Brain Injury: Results from The IMPACT Study. (J Neurotrauma. 2007)

Prognostic Value of Secondary Insults in Traumatic Brain Injury: Results from The IMPACT Study. (J Neurotrauma. 2007)

Sleep-wake disturbances 6 months after traumatic brain injury: a prospective study. (Brain. 2007)

The association between the postconcussion symptoms and clinical outcomes for patients with mild traumatic brain injury. (J Trauma. 2007) "RESULTS: Physical symptoms such as dizziness and headache were prominent in the early after injury stage (1 and 2 weeks). On the other hand, the psychosocial symptoms, such as depression and irritability, were significant at the late after injury stage (4 and 8 weeks). Dizziness adversely affected clinical outcome at both the early and late stages of the disease, whereas the impact of intracranial lesions and depression on outcome was greatest early and late, respectively."

Traumatic brain injury and Alzheimer's disease: a review. (Prog Brain Res. 2007) "… there still appears to be an increasing trend to support the hypothesis that TBI is a potential risk factor for AD. Furthermore, although it is known that APOE genotype plays an important role in AD, its link to a deleterious outcome following TBI remains inconclusive and ambiguous."

Traumatic brain injury-mediated hypopituitarism. Report of four cases. (Eur J Pediatr. 2007) "Hypopituitarism has been increasingly recognised following traumatic brain injury."

[Traumatic brain injury--pathophysiology and clinic seen from a neurosurgical point of view] (/a> (Ugeskr Laeger. 2007) "Traumatic brain injury (TBI) can be divided into primary and secondary brain damage. The primary damage occurs at the time of impact, induces neuronal death and is refractory to treatment. The secondary damage occurs at some time after the impact, has extracranial (hypoxia/hypotension) and intracranial (haematomas/swelling) causes and is largely preventable and treatable."

Traumatic head injury in infants and toddlers. (Acta Paediatr. 2007)

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