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Sinusitis - Rhinosinusitis

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Sinusitis - Rhinosinusitis

Daily Treatment Report

Cognitive Therapy-CBT-Psychotherapy

Device Therapy

 

Drug Side-Effects and Interactions

 

Drugs

Antibiotics and Topical Nasal Steroid for Treatment of Acute Maxillary Sinusitis (JAMA. 2007) "Context Acute sinusitis is a common clinical problem that usually results in a prescription for antibiotics but the role of antibiotics is debated. Anti-inflammatory drugs such as topical steroids may be beneficial but are underresearched. … Conclusion Neither an antibiotic nor a topical steroid alone or in combination was effective as a treatment for acute sinusitis in the primary care setting."

Bacterial infection and antibiotic treatment in chronic rhinosinusitis. (Clin Allergy Immunol. 2007)

Steroids for acute sinusitis. (Cochrane Database Syst Rev. 2007) "AUTHORS' CONCLUSIONS: For acute sinusitis confirmed by radiology or nasal endoscopy, current evidence is limited, but supports the use of INCS as a monotherapy or as an adjuvant therapy to antibiotics. Clinicians should weigh the modest but clinically important benefits against possible minor adverse events when prescribing therapy."

Treatment of acute and chronic rhinosinusitis in the United States, 1999-2002. (Arch Otolaryngol Head Neck Surg. 2007) "CONCLUSIONS: The use of prescription antibiotics far outweighs the predicted incidence of bacterial causes of acute and chronic rhinosinusitis. Frequency of antibiotic class used was not congruent with reported antimicrobial efficacy of the respective classes. Despite contradictory efficacies reported in the literature, inhaled corticosteroids were frequently used to treat acute rhinosinusitis. Antibiotics and inhaled nasal corticosteroids are being used more often than their published efficacies would encourage."

Antibiotics Too Often Prescribed for Sinus Woes "U.S. doctors are consistently overprescribing antibiotics for sinus infections, a new study finds, but even the physician who led the research doesn't see how the problem can be eliminated. That's because when it comes to treatments for sinus trouble, antibiotics are the best of a bad lot, said Dr. Donald A. Leopold, chairman of the department of otolaryngology at the University of Nebraska Medical Center. … The problem is that antibiotics are effective only against bacteria, but many sinus infections are due to other causes, such as viral infections, allergies or hormonal changes. The often-repeated standard wisdom is that use of antibiotics in such cases should be avoided to reduce the emergence of dangerous resistant bacterial strains. "

Systemic corticosteroids for allergic fungal rhinosinusitis and chronic rhinosinusitis with nasal polyposis: A comparative study. (Otolaryngol Head Neck Surg. 2007) "CONCLUSION: Radiographic response of AFRS to systemic corticosteroids is significantly greater compared with CRSwNP. This finding is supported by endoscopic observation."

Exercise

General Information

Recommended and prescribed symptomatic treatment for acute maxillary sinusitis in Finnish primary care. (Rhinology. 2007) "We conclude that Finnish physicians recommend or prescribe more symptomatic medication without proven efficacy for AMS than recommended by the national guidelines. Especially, the use of antihistamines with or without sympathomimetics, mostly the combination of acrivastine and pseudoephedrine, was common although antihistamines were recommended only for patients with allergy or nasal polyps."

Bacterial infection and antibiotic treatment in chronic rhinosinusitis. (Clin Allergy Immunol. 2007)

Treatment of acute and chronic rhinosinusitis in the United States, 1999-2002. (Arch Otolaryngol Head Neck Surg. 2007) "CONCLUSIONS: The use of prescription antibiotics far outweighs the predicted incidence of bacterial causes of acute and chronic rhinosinusitis. Frequency of antibiotic class used was not congruent with reported antimicrobial efficacy of the respective classes. Despite contradictory efficacies reported in the literature, inhaled corticosteroids were frequently used to treat acute rhinosinusitis. Antibiotics and inhaled nasal corticosteroids are being used more often than their published efficacies would encourage."

Clinical outcomes of chronic rhinosinusitis in response to medical therapy: results of a prospective study. (Am J Rhinol. 2007) "CONCLUSION: The majority of CRS patients receiving medical treatment show modest improvement over time in SNOT-20+1 scores. Facial pain or facial pressure at entry are negatively associated with outcomes and may reflect causes other than CRS. These findings highlight the limitations of current medical treatment for CRS and the need for novel treatment strategies."

An immunological approach to chronic and recurrent sinusitis. (Curr Opin Otolaryngol Head Neck Surg. 2007)

Guidelines

BSACI guidelines for the management of rhinosinusitis and nasal polyposis. (Clin Exp Allergy. 2007) “Rhinosinusitis implies inflammation of the nose and sinuses which may or may not have an infective component and includes nasal polyposis. Acute rhinosinusitis lasts up to 12 weeks and resolves completely. Chronic rhinosinusitis persists over 12 weeks and may involve acute exacerbations. Rhinosinusitis is common, affecting around 15% of the population and causes significant reduction in quality of life. The diagnosis is based largely on symptoms with confirmation by nasendoscopy. Computerized tomography scans and magnetic resonance imaging are abnormal in approximately one third of the population so are not recommended for routine diagnosis but should be reserved for those with acute complications, diagnostic uncertainty or failed medical therapy.”

Guidelines for the Diagnosis and Management of Rhinosinusitis in Adults (Am Fam Physician 2007)

Clinical practice guideline: adult sinusitis. (Otolaryngol Head Neck Surg. 2007)

Immunotherapy

 

Internet Sites

Treatment Information

DrugBank (drug structure)

FDA - MedWatch (Drug Alerts)

Drug-Food-Supplement Information

Drug Information Online

Drug Interaction Checker

DrugDigest (drug interactions)

FDA - Drug Interactions: What You Should Know

NIH - Botanical Dietary Supplements: Background Information

NIH - Drug, Supplements, and Herbal Information

NIH - Herbal Supplements: Consider Safety, Too

NIH - Medicines

NIH - Vitamin and Mineral Supplement Fact Sheets

Nutrition

 

Other

Other Treatments

Nasal saline for chronic sinonasal symptoms: a randomized controlled trial. (Arch Otolaryngol Head Neck Surg. 2007) “CONCLUSION: Nasal irrigations performed with large volume and delivered with low positive pressure are more effective than saline sprays for treatment of chronic nasal and sinus symptoms in a community-based population.”

Nasal saline irrigations for the symptoms of chronic rhinosinusitis. (Cochrane Database Syst Rev. 2007) "CONCLUSIONS: Saline irrigations are well tolerated. Although minor side effects are common, the beneficial effect of saline appears to outweigh these drawbacks for the majority of patients. The use of topical saline could be included as a treatment adjunct for the symptoms of chronic rhinosinusitis."

Experimental

Radiotherapy

 

Supplements-Vitamins-CAM

Surgery

Long-term effects of postoperative measures after sinus surgery. (Eur Arch Otorhinolaryngol. 2007)

[Endoscopic sinonasal surgery: study of 110 patients with nasal polyposis and chronic rhinosinusitis.] (Acta Otorrinolaringol Esp. 2007)

Influence of age on the surgical outcome after endoscopic sinus surgery for chronic rhinosinusitis with nasal polyposis. (Laryngoscope. 2007)

Comparative outcomes of endoscopic sinus surgery in patients with chronic sinusitis and nasal polyps. (Eur Arch Otorhinolaryngol. 2007)

Adult chronic rhinosinusitis: surgical outcomes and the role of endoscopic sinus surgery. (Curr Opin Otolaryngol Head Neck Surg. 2007) " SUMMARY: The data in the literature clearly support the use of functional endoscopic sinus surgery in cases of chronic rhinosinusitis refractory to medical therapy. Surgery has been shown to improve patient symptoms, quality of life and intranasal endoscopic exam."

Transplantation

 

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