Insomnia

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Insomnia

General Information

NEWS:

Insomnia may lead to toilet visits, study finds "Sleep deprivation reduced the usual dip in blood pressure that is seen at night, they found. This, in turn affected blood pressure-related substances such as rennin, angiotensin II and aldosterone, which could have in turn kept the kidneys on a daytime schedule, the researchers said."

Less Sleep, More Bathroom Trips "Lying awake at night increases urine production -- meaning more trips to the bathroom, especially for men, Danish researchers find. At night, urine production slows -- one of evolution's contributions to a good night's sleep. But what happens if you can't get to sleep? … On the sleepless nights, both men and women produced more urine than they did on the nights they slept. But this effect was more pronounced in the men than in the women."

Night Owls and Insomnia

Sleep hygiene helps patients catch some ZZZs

ARTICLES:

JOURNAL ARTICLES:

Asymptomatic insomnia. (Sleep Med. 2007)

A comparison of rates of residual insomnia symptoms following pharmacotherapy or cognitive-behavioral therapy for major depressive disorder. (J Clin Psychiatry. 2007) "CONCLUSION: Although CBT and pharmacotherapy effectively addressed depression in these patients and addressed insomnia symptoms for many, there were a number of patients with residual insomnia. Whereas there appears to be no difference between CBT and pharmacotherapy with regard to rates of residual insomnia, the rates of such insomnia remaining after these treatments suggest that adjunctive sleep treatment to specifically address insomnia may be necessary for some MDD patients."

Chronic insomnia as a risk factor for developing anxiety and depression. (Sleep. 2007)

Daytime napping after a night of sleep loss decreases sleepiness, improves performance, and causes beneficial changes in cortisol and interleukin-6 secretion (Am J Physiol Endocrinol Metab 2007) "Sleep loss has been associated with increased sleepiness, decreased performance, elevations in inflammatory cytokines, and insulin resistance. Daytime napping has been promoted as a countermeasure to sleep loss. … We conclude that a 2-h midafternoon nap improves alertness, and to a lesser degree performance, and reverses the effects of one night of sleep loss on cortisol and IL-6. The redistribution of cortisol secretion and the prolonged suppression of IL-6 secretion are beneficial, as they improve alertness and performance."

Inflammation and sleep in healthy individuals. (Sleep. 2007)

Preclinical cognitive decline and subsequent sleep disturbance in older women. (Neurology. 2007)

Prevalence and correlates of clinical insomnia co-occurring with chronic back pain. (J Sleep Res. 2007) "Significant positive correlations with insomnia severity were detected for all six variables of interest (pain intensity, sensory pain ratings, affective pain ratings, general anxiety, general depression and health anxiety). Affective pain ratings and health anxiety were the best predictors of insomnia severity in this sample, accounting for 30% of the total variance, even when present pain intensity was controlled for. Affective pain remained as a significant predictor of insomnia severity when both the effect of pain intensity and the effects of anxiety and depression were controlled for."

Prevalence and risk factors of subjective sleepiness in the general adult population. (Sleep. 2007)

Sleep Problems in Primary Care: A North Carolina Family Practice Research Network (NC-FP-RN) Study (The Journal of the American Board of Family Medicine 2007) "Conclusion: Sleep complaints are highly prevalent in primary care populations. Patients with the highest risk for sleep disturbance are those with pain, mental illness, limited activity, and overall "poor physical and mental health." Because sleep disorders are associated with a significant health impact, positive responses to questions regarding sleep symptoms should prompt further diagnostic inquiry."

The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults (Brain, Behavior, and Immunity 2007) "These findings suggest that one night of sleep loss triggers a stress response that includes stimulation of both pro- and anti-inflammatory proteins in the healthy young subjects tested under our experimental conditions."

The prevalence, morbidities, and treatments of insomnia. (CNS Neurol Disord Drug Targets. 2007) "Insomnia is a common condition that often is co-morbid with other illnesses. It is associated with significant morbidities, including nighttime distress, impaired cognitive functioning, impaired daytime functioning, and increased risk of accidents. People with insomnia utilize healthcare services more often than those without insomnia, and they are at greater risk for the development of certain health problems; most notably psychiatric illness such as depression."

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