Gastroesophageal Reflux Disease

• Diagnosis, Imaging, Screening
• General Information
• Guidelines
• Internet Sites
• Risk Factors
• Risk Reduction
• Treatment

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Gastroesophageal Reflux Disease

Daily Treatment Report

Cognitive Therapy-CBT-Psychotherapy

Device Therapy

Drug Side-Effects and Interactions

Symptoms in patients on long-term proton pump inhibitors: prevalence and predictors. (Aliment Pharmacol Ther. 2008)

Proton pump inhibitors: balancing the benefits and potential fracture risks

Use of proton pump inhibitors and risk of osteoporosis-related fractures (CMAJ 2008) “Interpretation: Use of proton pump inhibitors for 7 or more years is associated with a significantly increased risk of an osteoporosis-related fracture. There is an increased risk of hip fracture after 5 or more years exposure.”

Drugs

Effect of Proton-Pump Inhibitor Treatment on Symptoms and Quality of Life in GERD Patients Depends on the Symptom-reflux Association. (J Clin Gastroenterol. 2008)

Exercise

General Information

Recurring Symptoms Experienced By Nearly 40 Percent Of GERD Patients Taking PPIs "Despite daily use of doctor-recommended proton pump inhibitors (PPIs) to control gastroesophageal reflux disease (GERD) symptoms, nearly 40 percent of patients who take them continue to experience breakthrough, which is a return of GERD symptoms, such as acid regurgitation and heartburn. These breakthrough symptoms lead more than half of GERD sufferers to use over-the-counter (OTC) remedies, according to a survey recently conducted by the American Gastroenterological Association (AGA) Institute."

Meta-analysis: Sequential Therapy Appears Superior to Standard Therapy for Helicobacter pylori Infection in Patients Naive to Treatment (Annals 2008)

Fundoplication for gastroesophageal reflux and factors associated with the outcome 6 to 10 years after the operation: multivariate analysis of prognostic factors using the propensity score. (Surg Endosc. 2008)

Endoscopic Therapy of Gastroesophageal Reflux Disease: Outcomes of the Randomized-controlled Trials Done to Date. (J Clin Gastroenterol. 2008)

Guidelines

Guidelines Issued for Management of GERD

Evidence-Based GERD Guidelines Released By The American Gastroenterological Association

NGC - GUIDELINE SYNTHESIS - DIAGNOSIS AND TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE (GERD) (2007)

Immunotherapy

Internet Sites

Treatment Information

DrugBank (drug structure)

FDA - MedWatch (Drug Alerts)

Drug-Food-Supplement Information

Drug Information Online

Drug Interaction Checker

DrugDigest (drug interactions)

FDA - Drug Interactions: What You Should Know

NIH - Botanical Dietary Supplements: Background Information

NIH - Drug, Supplements, and Herbal Information

NIH - Herbal Supplements: Consider Safety, Too

NIH - Medicines

NIH - Vitamin and Mineral Supplement Fact Sheets

Nutrition

Other

Other Treatments

Experimental

Radiotherapy

Supplements-Vitamins-CAM

Surgery

Surgery Is Beneficial For Treatment Of Gastro-oesophageal Reflux

Long-term results of redo gastro-esophageal reflux disease surgery. (Eur J Cardiothorac Surg. 2008)

Transplantation

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