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Ankylosing Spondylitis
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NotesThe Guidelines section will contain 2008 and some 2007 updated published guidelines. To view Guidelines from previous years, view the Guideline sections or the Article sections or our Monthly Online Newsletter (under the Guidelines section). |
Ankylosing SpondylitisDaily Treatment ReportCognitive Therapy-CBT-Psychotherapy
Device Therapy
Drug Side-Effects and InteractionsDrugsInfliximab in severe active ankylosing spondylitis with spinal ankylosis (Intern Med J. 2008) ExerciseRehabilitation in ankylosing spondylitis. (Curr Opin Rheumatol. 2008) This review demonstrates the importance of continued emphasis on exercise therapy, the need for a standardized approach to exercise therapy, and a potential biologic effect. Exercise therapy should remain a mainstay of ankylosing spondylitis treatment complementing medical therapy.” General InformationRehabilitation in Ankylosing Spondylitis (Curr Opin Rheumatol. 2008) Nonsurgical management of ankylosing spondylitis. (Neurosurg Focus. 2008) Management of cervical deformity in ankylosing spondylitis (Neurosurgical Focus 2008) Nonsurgical management of ankylosing spondylitis (Neurosurgical Focus 2008) Medical management of ankylosing spondylitis (Neurosurgical Focus 2008) “ANKYLOSING spondylitis is a chronic, inflammatory rheumatic disease. Its pathogenesis involves the formation of syndesmophytes with resultant spinal ankylosis. The vertebral column transforms from a dynamic structure with ligamentous attachments into a rigid column of tubular bone housing the spinal cord and neural elements. Sacroiliitis, spondylitis, and enthesitis all contribute to characteristic inflammatory axial pain. Common extra-spinal manifestations of AS include peripheral arthritis (25–50%), uveitis (25–40%), inflammatory bowel disease (26%), and psoriasis (10%).14…Treatment goals in AS center around 3 central principles: 1) symptom relief, 2) functionality relative to activities of daily living and work performance, and 3) delay or avoidance of the structural damage responsible for physical impairments or deformity. To this end, the ASAS International Working Group, in collaboration with the EULAR, developed consensus guidelines for the medical management of AS. Ten propositions, ranging from diagnosis to physical therapy and medical management, emerged from a 3-round Delphi exercise from a panel of experts; heavy consideration was given to supporting literature for various treatment modalities.15 In the following review we summarize the ASAS/ EULAR consensus recommendations and include a systematic discussion of relevant studies. Discussion will proceed from general considerations in AS, namely diagnosis and disease monitoring, to nonpharmacological management tools and available medications. Surgical management of AS will be discussed elsewhere.” GuidelinesNGC - Adalimumab, etanercept and infliximab for ankylosing spondylitis. (2008) Immunotherapy
Internet SitesTreatment Information Drug-Food-Supplement Information DrugDigest (drug interactions) FDA - Drug Interactions: What You Should Know NIH - Botanical Dietary Supplements: Background Information NIH - Drug, Supplements, and Herbal Information NIH - Herbal Supplements: Consider Safety, Too NIH - Vitamin and Mineral Supplement Fact Sheets Nutrition
OtherOther Treatments Physiotherapy interventions for ankylosing spondylitis. (Cochrane Database Syst Rev. 2008) Experimental Radiotherapy
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Transplantation
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