Bipolar Disorder
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Bipolar Disorder
NIH - Medical Encyclopedia Bipolar disorder
"There are two primary types of bipolar disorder. People with bipolar disorder I have had at least one fully manic episode with periods of major depression. (In the past, bipolar disorder I was called manic depression.) People with bipolar disorder II seldom experience full-fledged mania. Instead they experience periods of hypomania (elevated levels of energy and impulsiveness that are not as extreme as the symptoms of mania). These hypomanic periods alternate with episodes of major depression."
Highlighted ArticleClinical features of bipolar depression versus major depressive disorder in large multicenter trials. (Am J Psychiatry. 2006)
"RESULTS: Bipolar depression was associated with family history of bipolar disorder, an earlier age at onset, a greater previous number of depressive episodes … Fears were more common in patients with bipolar disorder, whereas sadness; insomnia; intellectual (cognitive), somatic (muscular), respiratory, genitourinary complaints; and depressed behavior were more common in patients with unipolar depression."
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Notes
The Guidelines section will contain 2008 and some 2007 updated published guidelines. To view Guidelines from previous years, view the Guideline sections or the Article sections or our Monthly Online Newsletter (under the Guidelines section).
Bipolar Disorder
Daily Treatment Report
Cognitive Therapy-CBT-Psychotherapy
Drug Side-Effects and Interactions
Antipsychotic-induced extrapyramidal side effects in bipolar disorder and schizophrenia: a systematic review. (J Clin Psychopharmacol. 2008)
Drugs
Lithium: Bipolar disorder and neurodegenerative diseases Possible cellular mechanisms of the therapeutic effects of lithium. (Prog Neuropsychopharmacol Biol Psychiatry. 2008)
Quetiapine and classical mood stabilizers in the long-term treatment of Bipolar Disorder: A 4-year follow-up naturalistic study. (J Affect Disord. 2008)
Lamotrigine in the acute treatment of bipolar depression: results of five double-blind, placebo-controlled clinical trials. (Bipolar Disord. 2008)
Olanzapine for the treatment of bipolar disorder in children and adolescents. (Expert Opin Pharmacother. 2008)
Exercise
General Information
What is the optimal serum lithium level in the long-term treatment of bipolar disorder - a review? (Bipolar Disorders 2008) "Conclusions: In the long-term treatment of bipolar disorder clinicians should initially aim for serum lithium levels of 0.6-0.75 mmol/L, while higher levels may benefit patients with predominantly manic symptoms."
Guidelines
Internet Sites
Treatment Information
Drug-Food-Supplement Information
DrugDigest (drug interactions)
FDA - Drug Interactions: What You Should Know
NIH - Botanical Dietary Supplements: Background Information
NIH - Drug, Supplements, and Herbal Information
NIH - Herbal Supplements: Consider Safety, Too
NIH - Vitamin and Mineral Supplement Fact Sheets
Nutrition
Other
Other Treatments
Experimental
Supplements-Vitamins-CAM
Omega-3 fatty acids for bipolar disorder. (Cochrane Database Syst Rev. 2008)
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