Colorectal Cancer
- Diagnosis, Imaging, Screening
- General Information
- Guidelines
- Internet Sites
- Risk Factors
- Risk Reduction
- Treatment
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Notes
The Guidelines section will contain 2008 and some 2007 updated published guidelines. To view Guidelines from previous years, view the Guideline sections or the Article sections or our Monthly Online Newsletter (under the Guidelines section).
Colorectal Cancer
Daily Treatment Report
Cognitive Therapy-CBT-Psychotherapy
Device Therapy
Drug Side-Effects and Interactions
A review on oxaliplatin-induced peripheral nerve damage. (Cancer Treat Rev. 2008) "Platinum compounds are a class of chemotherapy agents that posses a broad spectrum of activity against several solid malignancies. Oxaliplatin (OXL) is a third-generation organoplatinum compound with significant activity mainly against colorectal cancer (CRC). Peripheral neuropathy is a well recognized toxicity of OXL, usually resulting in dose modification. OXL induces two types of peripheral neuropathy; acute and chronic."
Drugs
The Effect of Aspirin in the Recurrence of Colorectal Adenomas: A Meta-analysis of Randomized Controlled Trials. (Colorectal Dis. 2008)
Irinotecan in the treatment of elderly patients with advanced colorectal cancer. (Crit Rev Oncol Hematol. 2008)
Adjuvant Therapy for completely resected Stage II Colon Cancer. (Cochrane Database Syst Rev. 2008)
Colorectal Cancer Drugs Require Careful Patient Selection
Systemic treatment of colorectal cancer. (Gastroenterology. 2008)
Exercise
General Information
Removing small colon polyps costly, unnecessary “The surgical removal of small colon polyps found during computed tomography imaging of the colon, or CT colonography, is costly and unnecessary, according to a new study. "We shouldn't aggressively pursue sub-centimeter lesions, since the costs, risks, and inconvenience of the subsequent colonoscopy outweighs the clinical importance of these small polyps," Dr. Perry J. Pickhardt from University of Wisconsin School of Medicine and Public Health in Madison told Reuters Health. "Over time, the few small polyps that matter will declare themselves by showing interval growth," the researcher added. Colonoscopy is a colorectal cancer screening test performed with a small camera and under sedation that allows doctors to detect precancerous growths in the colon and remove them on the spot.“
Local recurrence after curative resection in patients with colon and rectal cancers. (Int J Colorectal Dis. 2008) “CONCLUSION: Compulsive follow-up care of patients with colon and rectal cancers is needed for 3 years after curative resection, especially in patients who have adverse risk factors for local recurrence.”
Circulating 25-Hydroxyvitamin D Levels and Survival in Patients With Colorectal Cancer (Journal of Clinical Oncology 2008) “Conclusion: Among patients with colorectal cancer, higher prediagnosis plasma 25(OH)D levels were associated with a significant improvement in overall survival.”
Dairy products, polymorphisms in the vitamin D receptor gene and colorectal adenoma recurrence. (Int J Cancer. 2008)
Advanced Colon Cancer: Administering Calcium And Magnesium Effectively Reduces Neurological Sensitivity “Researchers in the North Central Cancer Treatment Group (NCCTG) have shown that patients who receive intravenous calcium and magnesium before and after the chemotherapy drug oxaliplatin for the treatment of advanced colon cancer experience a significantly reduced incidence and severity of neurological side effects (neurotoxicity). This reduction increases the likelihood that patients are able to complete a full course of treatment.”
Postpolypectomy colonoscopy surveillance guidelines: predictive accuracy for advanced adenoma at 4 years. (Ann Intern Med. 2008)
New Colon and Rectal Cancer Guidelines Chart Chemotherapy Options
Importance of postpolypectomy surveillance and postpolypectomy compliance to follow-up screening-review of literature. (Int J Colorectal Dis. 2008) "CONCLUSION: In conclusion, effective surveillance screening with good patient compliance in postpolypectomy patients will contribute significantly in reducing colon cancer morbidity and mortality."
Guidelines
Colonoscopy Surveillance After Polypectomy and Colorectal Cancer Resection: CONSENSUS GUIDELINES FROM THE U.S. MULTI-SOCIETY TASK FORCE ON COLORECTAL CANCER and THE AMERICAN CANCER SOCIETY (Am Fam Physician. 2008)
Colon:
National Comprehensive Cancer Network (NCCN) Colon Cancer and Rectal (Cancer Guidelines, Version 1.2008)
Rectal:
National Comprehensive Cancer Network (NCCN) Colon Cancer and Rectal (Cancer Guidelines, Version 1.2008)
Immunotherapy
Internet Sites
Treatment Information
NCI - Dictionary of Cancer Terms
NCI - Overview of Nutrition in Cancer Care
Drug-Food-Supplement Information
DrugDigest (drug interactions)
FDA - Drug Interactions: What You Should Know
NIH - Botanical Dietary Supplements: Background Information
NIH - Drug, Supplements, and Herbal Information
NIH - Herbal Supplements: Consider Safety, Too
NIH - Vitamin and Mineral Supplement Fact Sheets
Nutrition
Dietary flavonoids and colorectal adenoma recurrence in the polyp prevention trial. (Cancer Epidemiol Biomarkers Prev. 2008) “… high intake of flavonols, which are at greater concentrations in beans, onions, apples, and tea, was associated with decreased risk of advanced adenoma recurrence (4th versus 1st quartile during the trial; odds ratio, 0.24; 95% confidence interval, 0.11, 0.53; P(trend) = 0.0006). Similar inverse associations were observed to a smaller extent for isoflavonoids, the flavonol kaempferol, and the isoflavonoids genistein and formononetin. Our data suggest that a flavonol-rich diet may decrease the risk of advanced adenoma recurrence.”
Other
Radiation-Chemotherapy
Other Treatments
Experimental
Radiotherapy
Supplements-Vitamins-CAM
Surgery
"Keyhole" surgery OK for colon cancer “Surgical removal of colorectal cancer using minimally invasive laparoscopic techniques, commonly known as keyhole surgery, gives as good results as conventional open surgery, according to a new report.”
Advances in minimally invasive surgery in the treatment of colorectal cancer. (Expert Rev Anticancer Ther. 2008)
Transplantation
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