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MenopauseTreatment is updated with the most recent articles listed on top. REVIEW our Selected Menopause Articles in 2007. Stay informed and updated!
MenopauseNIH - Menopause “Menopause is the time in a woman's life when her period stops. It usually occurs naturally, most often after age 45. Menopause happens because the woman's ovary stops producing the hormones estrogen and progesterone. A woman has reached menopause when she has not had a period for one year. Changes and symptoms can start several years earlier. They include • A change in periods - shorter or longer, lighter or heavier, with more or less time in between • Hot flashes and/or night sweats • Trouble sleeping • Vaginal dryness • Mood swings • Trouble focusing • Less hair on head, more on face Menopause is not a disorder. Most women do not need treatment for it. However, if symptoms are severe, medicines may help. After menopause, women are more vulnerable to bone loss and heart disease. Exercise and eating right can help keep women healthy as they age.“ NIH – Menopause “Two common health problems can start to happen at menopause, and you might not even notice. Osteoporosis. Day in and day out, your body is busy breaking down old bone and replacing it with new healthy bone. Estrogen helps control bone loss, and losing estrogen around the time of menopause causes women to lose more bone than is replaced. In time, bones can become weak and break easily. This condition is called osteoporosis. Talk to your doctor to see if you should have a bone density test to find out if you are at risk. Your doctor can also suggest ways to prevent or treat osteoporosis. Heart disease. After menopause, women are more likely to have heart disease. Changes in estrogen levels may be part of the cause. But, so is getting older. As you age, you may gain weight and develop other problems, like high blood pressure. These could put you at greater risk for heart disease. Be sure to have your blood pressure and levels of triglycerides, fasting blood glucose, and LDL, HDL, and total cholesterol checked regularly. Talk to your health care provider to find out what you should do to protect your heart. How Can I Stay Healthy After Menopause? Staying healthy after menopause may mean making some changes in the way you live. • Don’t smoke. If you do use any type of tobacco, stop—it’s never too late to benefit from quitting smoking. • Eat a healthy diet, low in fat, high in fiber, with plenty of fruits, vegetables, and whole-grain foods, as well as all the important vitamins and minerals. • Make sure you get enough calcium and vitamin D—in your diet or with vitamin/mineral supplements. • Learn what your healthy weight is, and try to stay there. • Do weight-bearing exercise, such as walking, jogging, or dancing, at least 3 days each week for healthy bones. But try to be physically active in other ways for your general health. “ NIH – Menopause (Medical Encyclopedia) “Menopause is a natural event that normally occurs between the ages of 45 and 55. Once menopause is complete (called postmenopause), you can no longer become pregnant. The symptoms of menopause are caused by changes in estrogen and progesterone levels. As the ovaries become less functional, they produce less of these hormones and the body responds accordingly. The specific symptoms you experience and how significant (mild, moderate, or severe) varies from woman to woman. In some women, menstrual flow comes to a sudden halt. More commonly, it tapers off. During this time, your menstrual periods generally become either more closely or more widely spaced. This irregularity may last for 1 to 3 years before menstruation finally ends completely. A gradual decrease of estrogen generally allows your body to slowly adjust to the hormonal changes. When estrogen drops suddenly, as is seen when the ovaries are removed surgically (called surgical menopause), symptoms can be more severe. Because hormone levels fall, changes occur in the entire female reproductive system. The vaginal walls become less elastic and thinner. The vagina becomes shorter. Lubricating secretions from the vagina become watery. The outside genital tissue decreases. This is called atrophy of the labia.“ NHS – Menopause “Menopause myths • You can’t get pregnant after the menopause FALSE. It can and does happen so carry on using contraception for two years after your last period if you're under 50 and for one year if you're over 50. • You're going to put on weight FALSE. Middle-age-spread is often linked to the hormonal changes at this time of life but as yet there's no proof. Those extra inches could just be part of growing older and being less active. • Your menopause will be difficult because your mum’s was FALSE. There's no evidence to suggest this, although the age at which your mum went through hers could give you a clue as to when to expect symptoms, as the age of menopause tends to be similar in mums and daughters.” Highlighted Articles
Relationships between menopausal symptoms, depression, and exercise in middle-aged women: A cross-sectional survey (International Journal of Nursing Studies 2008) “Women who were depressed had more menopausal symptoms than women who were not depressed, and women who exercised regularly were less depressed and less symptomatic than women who did not exercise.” Dietary and lifestyle predictors of age at natural menopause and reproductive span in the Shanghai Women's Health Study. (Menopause. 2008) “RESULTS:: Early menarche, younger age at first live birth, older age at last live birth, longer duration of breast-feeding, and higher parity were associated with longer reproductive years (Ptrend < 0.01 for all). Higher body mass index at age 20, mid-life weight gain, and leisure-time physical activity during adolescence and adulthood predicted later menopause and longer reproductive span (Ptrend < 0.01 for all). Total intake of calories, fruits, and protein was positively associated with later menopause (Ptrend < 0.05 for all) and longer reproductive span (Ptrend < 0.05), except for carbohydrates (Ptrend = 0.06), and long-term tea consumption predicted longer reproductive span (Ptrend = 0.03). Vegetable, fat, soy, and fiber intakes did not significantly affect reproductive span or age at menopause. Smoking was inversely associated with both early age at menopause and shorter reproductive span (Ptrend < 0.01). CONCLUSIONS:: In addition to reproductive factors, intake of fruits and protein, smoking, tea consumption, lifetime patterns of physical activity, and weight gain influenced the onset of menopause and/or reproductive span in Chinese women.” Night sweats, sleep disturbance, and depression associated with diminished libido in late menopausal transition and early postmenopause: baseline data from the Herbal Alternatives for Menopause Trial (HALT). (Am J Obstet Gynecol. 2007) "RESULTS: Of 341 women, 64% had diminished libido, 18% had moderate to severe depression, and 43% had poor sleep quality. Women averaged 4.6 hot flashes and 1.9 night sweats per day. Depressive symptoms (P = .003), poor sleep (P = .02), and night sweats (P = .04) were significantly associated with diminished libido." The timing of natural menopause in Poland and associated factors. (Maturitas. 2007) " RESULTS: The overall median age at natural menopause was 51.25 years; 25th percentile 49; 75th percentile 54 years." Severe Hot Flashes May Be Linked to Chronic Insomnia (2007) "Hot flashes occurred in 12.5% of premenopausal women, 79.0% of perimenopausal women, and 39.3% of postmenopausal women. Chronic insomnia occurred in 36.5% of premenopausal women, 56.6% of perimenopausal women, and 50.7% of postmenopausal women (P < .001). Prevalence of symptoms of chronic insomnia increased with the severity of hot flashes. More than 80% of perimenopausal women and postmenopausal women who had severe hot flashes also had symptoms of chronic insomnia." CONTINUE YOUR INFOMEDSEARCH RESEARCH with our previous InfoMedLinks. Start with InfoMedLinks 2007.
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NotesThe Guidelines section will contain 2008 and some 2007 updated published guidelines. To view Guidelines from previous years, view the Guideline sections or the Article sections or our Monthly Online Newsletter (under the Guidelines section). |
MenopauseDaily Treatment ReportCognitive Therapy-CBT-PsychotherapyDevice Therapy
Drug Side-Effects and InteractionsPostmenopausal Hormone Use and Symptoms of Gastroesophageal Reflux (Arch Intern Med. 2008) “Conclusions Postmenopausal use of estrogens, selective estrogen receptor modulators, or OTC hormone preparations is associated with a greater likelihood of symptoms of GERD. This suggests a hormonal component to the pathophysiologic characteristics of GERD in women.” Estrogens, oral contraceptives and hormonal replacement therapy increase the incidence of cutaneous melanoma: a population-based case-control study. (Ann Oncol. 2008) “CONCLUSION: Our study suggests a cumulative dose-dependent increased risk of CM with the use of estrogens.” Effects of Estrogen With and Without Progestin and Obesity on Symptomatic Gastroesophageal Reflux (Gastroenterology 2008) “Conclusions: Estrogen treatment alone, but not with progestin, may cause GER symptoms in postmenopausal women. Increasing weight and girth increases the risk of developing GER symptoms, whereas weight loss alleviates existing GER symptoms.” HRT study 'highlights pills risk' “Using patches instead of pills could cut the risk of one of the lesser-known complications of hormone replacement therapy, a study of 1m women says. Some women on HRT develop gallbladder problems which require surgery to remove the organ. An Oxford University team reported the rate of operations for patch-wearers was substantially lower than for those having HRT in pill form. One could be avoided for every 140 people changing to patches, they said. The gallbladder is a small organ, attached to the base of the liver, which stores and concentrates bile, a substance which helps the body digest fat. Gallbladder diseases such as cholelithiasis or cholecystitis are generally more common in post-menopausal women, and HRT is known to increase the risk.” HRT pills 'blood clot risk link' HRT Increases Stroke Risk “No matter when postmenopausal women start hormone replacement therapy (HRT), high doses of the treatment increase their risk of stroke, a new study finds. The risk for stroke does appear lower in younger women taking HRT and in those taking the lowest doses of estrogen, Harvard researchers say. However, in women who took high doses of hormones, that increased risk was as much as 62 percent. "If you take medium to higher doses of hormone therapy, you are at increased risk of stroke," said Dr. James Liu, chairman of the Department of Obstetrics and Gynecology at MacDonald Women's Hospital, University Hospitals Case Medical Center in Cleveland. "If you are on estrogen, the risks of clotting abnormalities are slightly increased versus if you are not on estrogen," Liu said. "So, the risk of stroke is increased." “ Hormone Replacement Therapy Increases Risk For Breast Scan Abnormalities "Hormone replacement therapy (HRT) "could increase the risk of developing early signs of breast cancer after only one year", The Daily Telegraph reports. One of the largest studies of its kind has shown that "the group taking the hormones had a 4% greater risk of having an abnormal mammogram, or breast X-ray, than those taking the placebo", the newspaper said. There has been ongoing debate about the risks and benefits associated with HRT. It is known to cause a slight increase in the risk of breast cancer if taken for longer than five years. This news report will no doubt raise concerns among many women taking, or considering taking, HRT. The report is based on data from a large Women's Health Initiative (WHI) study in the US." HRT Hampers Accuracy Of Breast Cancer Tests, New Analysis Says "Postmenopausal women taking combined hormone replacement therapy have only a slightly higher risk of developing breast cancer, but there are much greater chances they will experience the worry of abnormal mammograms or undergo an avoidable breast biopsy than postmenopausal women not taking the drugs, according to a study published Monday, the San Francisco Chronicle reports. In addition, the tools used to diagnose breast cancer are less likely to catch malignant tumors in women taking combined HRT, despite the slightly increased risk of cancer, according to the study. Although the findings are "another small mark" against HRT, physicians said the study should not stop women from taking the drugs to alleviate menopausal and postmenopausal symptoms, especially if the symptoms are severe, the Chronicle reports (Allday, San Francisco Chronicle, 2/26)." DrugsTestosterone therapy for sexual dysfunction in postmenopausal women (Climacteric 2008) ExerciseTreating the climacteric symptoms in Indian women with an integrated approach to yoga therapy: a randomized control study. (Menopause. 2008) Exercise cuts heart risk in women "Aerobic exercise reduces the risk of heart disease and stroke in postmenopausal women, irrespective of whether they are using hormone replacement therapy (HRT) or not, the results of a new study indicate. According to the findings, this type of exercise reduces the chemical imbalances that can lead to these serious conditions. The US researchers explained that these chemical imbalances, known as oxidative stress, occur when oxidants outnumber antioxidants in the body. Oxidants are harmful chemicals that damage tissue and cells, while antioxidants protect cells and tissues against these oxidants. Postmenopausal women have higher levels of oxidative stress." Minimal Exercise Benefits Overweight Postmenopausal Women "Just 10 minutes to 30 minutes of exercise a day can improve the quality of life for sedentary, overweight or obese women, American researchers suggest." General InformationThe effects of tibolone in older postmenopausal women. (N Engl J Med. 2008) Testosterone unproven as yet for women's sex woes “Women should not take testosterone to treat loss of sexual desire until there is good evidence it is safe -- and that it actually works -- a behavioral scientist warns in a new report. "I think that there is a lot of excitement about the use of androgens ('male' hormones) to treat low sexual desire in women that is based on evidence that looks better than it really is," Dr. Leslie R. Schover told Reuters Health. "I think that the evidence has some significant flaws." “Less Swedish Women Getting Breast Cancer “The Swedish government says a reduction in hormonal therapy has resulted in fewer cases of breast cancer among women 45 and older.” Mayo Clinic and North Central Cancer Treatment Group hot flash studies: a 20-year experience. (Menopause. 2008) GuidelinesNAMS Updates Guidelines on Postmenopausal Hormone Therapy Immunotherapy
Internet SitesTreatment Information Drug-Food-Supplement Information DrugDigest (drug interactions) FDA - Drug Interactions: What You Should Know NIH - Botanical Dietary Supplements: Background Information NIH - Drug, Supplements, and Herbal Information NIH - Herbal Supplements: Consider Safety, Too NIH - Vitamin and Mineral Supplement Fact Sheets NutritionFlaxseed Reduces Total and LDL Cholesterol Concentrations in Native American Postmenopausal Women. (J Womens Health (Larchmt). 2008) OtherOther Treatments Experimental RadiotherapySupplements-Vitamins-CAMBlack cohosh (Cimicifuga racemosa) for menopausal symptoms: A systematic review of its efficacy. (Pharmacol Res. 2008) Surgery
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