PTSD and Panic, Anxiety, and Obsessive-Compulsive Disorders
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PTSD and Panic, Anxiety, and Obsessive-Compulsive Disorders
NIH - Medical Encyclopedia: Post-traumatic stress disorder
"Post-traumatic stress disorder is a psychiatric illness that can occur following a traumatic event in which there was threat of injury or death to you or someone else. … (PTSD) may occur soon after a major trauma, or can be delayed for more than six months after the event. When it occurs soon after the trauma it usually resolves after three months, but some people experience a longer-term form of the condition, which can last for many years. … People with PTSD re-experience the event again and again in at least one of several ways. They may have recurrent distressing dreams and recollections of the event, a sense of reliving the experience (referred to as flashbacks), and/or become very distressed around the time of events that symbolize the event (such as anniversaries)."
Highlighted Article
Posttraumatic Stress Disorder and Health Status: The Veterans Health Study. (J Ambul Care Manage. 2006)
"The association of PTSD with health status was substantial, suggesting that the burden of PTSD is at least comparable to, and may be worse than, that of depression. Mental health treatment alleviated some of this burden. The potential impact of PTSD on health status should be more widely recognized."
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PTSD and Panic, Anxiety, and Obsessive-Compulsive Disorders
Diagnosis, Imaging, and Screening
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JOURNAL ARTICLES:
Corpus Callosum in Patients with Obsessive-Compulsive Disorder: Diffusion-Tensor Imaging Study. (Radiology. 2008)
Gray matter structural alterations in obsessive–compulsive disorder: Relationship to neuropsychological functions (Psychiatry Research: Neuroimaging 2008) “Our findings provide additional support for the involvement of cortical–striatal–thalamic circuits in the pathophysiology of OCD and preliminary evidence that a defect involving the dorsolateral prefrontal cortex may also be implicated. Moreover, our data suggest that gray matter structural alterations in OCD have neuropsychological correlates, which may be useful in further characterizing structure–function relations in this disorder.”
Hippocampal and amygdala volumes in children and adults with childhood maltreatment-related posttraumatic stress disorder: A meta-analysis. (Hippocampus. 2008)
Increased prevalence of white matter hyperintensities in patients with panic disorder. (J Psychopharmacol. 2008)
Meta-Analysis of Brain Volume Changes in Obsessive-Compulsive Disorder. (Biol Psychiatry. 2008) “CONCLUSIONS: Our findings indicate volumetric differences between OCD patients and control subjects in the cortical and thalamic regions, suggesting that structural alteration of the thalamocortical pathways may contribute to the functional disruptions of frontosubcortical circuits observed in OCD.”
White Matter Abnormalities in Patients With Obsessive-Compulsive Disorder and Their First-Degree Relatives. (Am J Psychiatry. 2008)
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