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Sleep Apnea

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The Guidelines section will contain 2008 and some 2007 updated published guidelines. To view Guidelines from previous years, view the Guideline sections or the Article sections or our Monthly Online Newsletter (under the Guidelines section).

Sleep Apnea

Daily Treatment Report

Cognitive Therapy-CBT-Psychotherapy

 

Device Therapy

CPAP Can Curb Cardiac Risk in Patients With Sleep Apnea and Metabolic Syndrome “Continuous positive airway pressure (CPAP) reduced cardiovascular disease risk factors in patients with severe obstructive sleep apnea (OSA) and metabolic syndrome, but only in those with good adherence to the intervention, Slovakian researchers report in the October issue of Chest. The authors say the study is the first to analyze the effects of CPAP on glucose and lipid metabolism, systemic inflammation, oxidative stress, and overall cardiovascular disease (CVD) risk in a single group of patients with severe OSA and concurrent metabolic syndrome.“

Effects of CPAP on Cardiovascular Risk Profile in Patients with Severe Obstructive Sleep Apnea and Metabolic Syndrome. (Chest. 2008)

CPAP Reduces Mortality, Morbidity in Heart Failure With Sleep Apnea ""Our study found that CPAP treatment for patients with obstructive sleep apnea and heart failure reduced hospitalization as well as mortality rates," lead investigator Dr. Takatoshi Kasai told Reuters Health, "and that the risk of morbidity and mortality was increased with decreasing compliance." "

Drug Side-Effects and Interactions

 

Drugs

Exercise

General Information

Guidelines

NGC - Continuous positive airway pressure for the treatment of obstructive sleep apnoea/hypopnoea syndrome. (2008)

Guidelines Issued for Positive Airway Pressure Titrations in Obstructive Sleep Apnea

Immunotherapy

 

Internet Sites

Treatment Information

DrugBank (drug structure)

FDA - MedWatch (Drug Alerts)

Drug-Food-Supplement Information

Drug Information Online

Drug Interaction Checker

DrugDigest (drug interactions)

FDA - Drug Interactions: What You Should Know

NIH - Botanical Dietary Supplements: Background Information

NIH - Drug, Supplements, and Herbal Information

NIH - Herbal Supplements: Consider Safety, Too

NIH - Medicines

NIH - Vitamin and Mineral Supplement Fact Sheets

Nutrition

Green tea may shield brain from sleep apnea effects “Compounds found in green tea may help ward off the neurological damage that can come with the breathing disorder sleep apnea, a new animal study hints. Researchers found that when they added green tea antioxidants to rats' drinking water, it appeared to protect the animals' brains during bouts of oxygen deprivation designed to mimic the effects of obstructive sleep apnea (OSA). The findings suggest that green tea compounds should be further studied as a potential OSA therapy, the researchers report in the American Journal of Respiratory and Critical Care Medicine. OSA is a common disorder in which soft tissues in the throat temporarily collapse and block the airway during sleep, causing repeated stops and starts in breathing throughout the night. The immediate symptoms include chronic loud snoring and gasping, as well as daytime sleepiness. Left untreated, OSA can eventually have widespread effects in the body; it's linked to high blood pressure, and research suggests that the intermittent dips in oxygen to the brain may lead to memory and learning difficulties.“

Other

Other Treatments

Experimental

Omega-3 Fatty Acids Inversely Related to Sleep Apnea Severity “The investigators stopped short of saying that omega-3 supplementation, such as fish oil or flaxseed oil, might improve AHI scores and decrease the severity of sleep apnea, "but that is the next logical step," said Charles Atwood, MD, Associate Professor of Medicine at the University of Pittsburgh, in Pennsylvania, and Director of Sleep Medicine at the Veterans Affairs Medical Center in Pittsburgh, in an interview with Medscape Pulmonary Medicine during the meeting. "The findings are interesting but not surprising," Dr. Atwood commented. "They are consistent with other studies that show that sleep apnea causes oxidative stress and puts severe demands on the body. Omega-3 protects against stress, and this kind of long-term stress depletes those levels." "Studies of vitamins C and E and other antioxidants in patients with sleep apnea haven't yielded much just yet," Dr. Atwood noted, "and there are no clinical treatment indications at this point, but supplementation makes sense in disorders where antioxidants are used up." “

Radiotherapy

Supplements-Vitamins-CAM

Surgery

Groaning In Sleep Can Be Successfully Treated With CPAP, Study Shows "Catathrenia, or sleep related groaning, is an uncommon feature of a sleep-related breathing disorder that can be successfully treated with continuous positive airway pressure (CPAP), according to a recent study."

Surgery Not the Best Option for Sleep Apnea: Study "The researchers report the findings of a literature review on upper-airway surgery. One of these studies - a Cochrane review of 7 randomized trials - concluded that surgery had little impact on symptoms and that even where improvements in quality of life were shown immediately after surgery, these improvements were rarely sustained beyond 12 to 24 months. Another review of 48 studies concluded that up to 62% of 21,346 surgery patients reported persistent adverse effects such as dry throat, globus sensation, difficulty swallowing, voice changes, and disturbances of smell and taste. Up to 22% of these patients regretted having the surgery. Yet another review of 18 surgical studies found the success rate was as low as 13% for some types of surgery."

Transplantation

 

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