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Supplements - Nutrition
Melatonin
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Cardiovascular diseases: protective effects of melatonin. (J Pineal Res. 2008) “These findings have implications for the protective effects of melatonin against cardiac diseases induced by oxidative stress. Melatonin attenuates molecular and cellular damages resulting from cardiac ischemia/reperfusion in which destructive free radicals are involved. Anti-inflammatory and antioxidative properties of melatonin are also involved in the protection against a chronic vascular disease, atherosclerosis. The administration of melatonin, as a result of its antioxidant features, has been reported to reduce hypertension and cardiotoxicity induced by clinically used drugs. The results described herein help to clarify the beneficial effects of melatonin against these conditions and define the potential clinical applicability of melatonin in cardiovascular diseases.”
Dual effects of melatonin on oxidative stress after surgical brain injury in rats. (J Pineal Res. 2008)
Melatonin to prevent migraine or tension-type headache in children. (Neurol Sci. 2008)
Protective effect of melatonin against hippocampal injury of rats with intermittent hypoxia. (J Pineal Res. 2008) “Obstructive sleep apnea (OSA) patients suffer from intermittent hypoxia (IH) and neuropsychologic impairments. Oxidative stress is involved in the pathogenesis of OSA, so the application of an antioxidant may be useful. We evaluated the hypothesis that melatonin would reduce IH-induced hippocampal injury via an increased expression of antioxidant enzymes.”
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