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Bipolar Disorder

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Bipolar Disorder

NIH - Medical Encyclopedia Bipolar disorder

"There are two primary types of bipolar disorder. People with bipolar disorder I have had at least one fully manic episode with periods of major depression. (In the past, bipolar disorder I was called manic depression.) People with bipolar disorder II seldom experience full-fledged mania. Instead they experience periods of hypomania (elevated levels of energy and impulsiveness that are not as extreme as the symptoms of mania). These hypomanic periods alternate with episodes of major depression."

Highlighted Article

Clinical features of bipolar depression versus major depressive disorder in large multicenter trials. (Am J Psychiatry. 2006)

"RESULTS: Bipolar depression was associated with family history of bipolar disorder, an earlier age at onset, a greater previous number of depressive episodes … Fears were more common in patients with bipolar disorder, whereas sadness; insomnia; intellectual (cognitive), somatic (muscular), respiratory, genitourinary complaints; and depressed behavior were more common in patients with unipolar depression."



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Notes

View Treatment Guidelines from previous years. Go to Treatment for each year.

Bipolar Disorder

Daily Treatment Report

Cognitive Therapy-CBT-Psychotherapy

Drug Side-Effects and Interactions

Drugs

Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial (The Lancet 2009)

Lithium Beats Valproate for Long-Term Bipolar Therapy “People with bipolar I disorder will do best over the long term with lithium treatment alone or a combination of lithium and valproate compared to valproate alone, new research suggests. Patients who underwent the lithium or lithium/valproate treatments were less likely to relapse regardless of how severe their conditions were at the beginning of treatment, the study authors reported in the Dec. 22 online edition of The Lancet.”

Olanzapine in long-term treatment for bipolar disorder. (Cochrane Database Syst Rev. 2009)

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General Information

Does cannabis use affect treatment outcome in bipolar disorder? A longitudinal analysis. (J Nerv Ment Dis. 2009)

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