Depression

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Depression

NIH - Medical Encyclopedia Depression

"Depression may be described as feeling sad, blue, unhappy, miserable, or down in the dumps. Most of us feel this way at one time or another for short periods. But true clinical depression is a mood disorder in which feelings of sadness, loss, anger, or frustration interfere with everyday life for an extended time. … The main types of depression include: Major depression -- five or more symptoms listed above must be present for at least 2 weeks, but major depression tends to continue for at least 6 months. (Depression is classified as minor depression if less than five depressive symptoms are present for at least 2 weeks.) and Dysthymia -- a chronic, generally milder form of depression but lasts longer -- usually as long as two years. Depression also includes atypical depression, postpartum depression, Premenstrual dysphoric disorder (PMDD), and Seasonal affective disorder (SAD). … If you are depressed for 2 weeks or longer, you should contact your doctor, who can offer treatment options. … Call 911, a suicide hotline, or get safely to a nearby emergency room if you have thoughts of suicide, a suicidal plan, or thoughts of harming yourself or others."

Highlighted Article

Regular exercise, anxiety, depression and personality: A population-based study. (Prev Med. 2006)

"This study corroborates and extends previous findings: regular exercise is cross-sectionally associated with lower neuroticism, anxiety and depression and higher extraversion and sensation seeking in the population."

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Depression

Daily Treatment Report

In this Report:

Cognitive Therapy-CBT-Psychotherapy
Device Therapy
Drug Side-Effects and Interactions
Drugs
Exercise
General Information
Guidelines
Immunotherapy
Internet Sites
Nutrition
Other
Radiotherapy
Supplements-Vitamins-CAM
Surgery
Transplantation

Cognitive Therapy-CBT-Psychotherapy

Online CBT May Be Better Than Usual Care for Depression

Device Therapy

Drug Side-Effects and Interactions

Antidepressants May Change Your Personality

Increased Risk of Death, Stroke in Postmenopausal Women Taking Antidepressants, Study Finds

Postmenopausal Woman and Antidepressants: Deadly Combination? “Postmenopausal women who take antidepressants may have a greater risk of stroke or death, new research shows.”

Selective serotonin reuptake inhibitors in pregnancy and congenital malformations: population based cohort study (BMJ 2009) “Conclusion There is an increased prevalence of septal heart defects among children whose mothers were prescribed an SSRI in early pregnancy, particularly sertraline and citalopram. The largest association was found for children of women who redeemed prescriptions for more than one type of SSRI.”

New Study Shows the SSRI Paroxetine May Affect Sperm DNA and Male Fertility “The selective serotonin-reuptake inhibitor (SSRI) paroxetine (Paxil, GlaxoSmithKline) may affect male fertility through its effects on sperm DNA, according to a small study by Weill Cornell Medical Center researchers. In the study of 35 healthy volunteers without psychiatric disorders, the antidepressant induced abnormal sperm DNA fragmentation in more than 40% of participants.”

Use of antidepressants and the risk of Parkinson's disease: a prospective study. (J Neurol Neurosurg Psychiatry. 2009)

Some Antidepressants May Risk Breast Cancer Return

Depression and Antidepressant Use Linked to Sudden Cardiac Death in Women “Whang told heartwire that he believes the biggest clinical implication of this new study "is that management of coronary heart disease risk factors may be especially important among women with depressive symptoms."”

Depression Is Associated With Decreased Blood Pressure, but Antidepressant Use Increases the Risk for Hypertension (Hypertension 2009) “Users of noradrenergic and serotonergic working antidepressants were more likely to have hypertension stage 1. This study shows that depressive disorder is associated with low systolic blood pressure and less hypertension, whereas the use of certain antidepressants is associated with both high diastolic and systolic blood pressures and hypertension.”

SSRI Exposure in Pregnancy May Increase Gestational Hypertension Risk "These findings suggest that "women who are exposed to SSRIs during pregnancy should be carefully monitored for the occurrence of gestational hypertension and preeclampsia," Sengwee Toh and colleagues write."