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Supplements - Nutrition

General Information - Vitamins and Supplements

NEWS:

Contaminants lurk in many ‘natural’ products

Long-Term Use Of Nutrient Supplements May Increase Cancer Risk “Long-term use of beta carotene and some other carotenoid-containing dietary supplements may increase the risk of lung cancer, especially among smokers, according to a study by University of North Carolina at Chapel Hill researchers. … The results show that smokers’ risk of developing lung cancer increased with the length of time they took dietary supplements containing beta carotene, retinol and lutein. “The risk increased the longer the person had taken the supplements,” Satia said. “The amount of time the person took supplements seemed to have a greater effect than the dose. Even a modest dose, if taken for a long time, can increase the risks of lung cancer, especially among smokers.” For example, the study found that use of retinol and lutein supplements for four years or longer was associated with increases in lung cancer risk of 53 percent and 102 percent, respectively. The risk for nonsmokers could not be determined because lung cancer cases among nonsmokers was small, Satia said. “We believe beta-carotene is an antioxidant, but it seems that if you take too much, at some point it can have pro-oxidant effects, which can result in elevated cancer risk.” “

Most men are deficient in key minerals and vitamins.

Multivitamins Might Prolong Life “Multivitamins may help women live longer by preventing parts of their DNA from shortening, a new study has found. Telomeres, or the end portion of chromosomes, protect chromosomes from damage. Because telomeres shorten slightly when cells divide, researchers speculated that preventing this shortening could protect new cells and thus reduce the effects of aging. "This study provides the first epidemiological evidence that multivitamin use is associated with longer leukocyte telomeres among women," said lead researcher Dr. Honglei Chen, head of the Aging & Neuroepidemiology Group at the U.S. National Institute of Environmental Health Sciences. "It is not yet clear if this association is causal." “

Multivitamins no cancer, heart help, study says “The study's lead author, researcher Marian Neuhouser of the Fred Hutchinson Cancer Research Center in Seattle, offered this advice: "Get nutrients from food. Whole foods are better than dietary supplements," Neuhouser said. … Co-author Dr. JoAnn Manson said despite the disappointing results, the research doesn't mean multivitamins are useless. For one thing, the data are observational, not the most rigorous kind of scientific research. And also, it's not clear if taking vitamins might help prevent cancers that take many years to develop, said Manson, chief of preventive medicine at Harvard's Brigham & Women's Hospital. She said multivitamins may still be useful "as a form of insurance" for people with poor eating habits.”

ARTICLES:

JOURNAL ARTICLES:

Multivitamin Use and Risk of Cancer and Cardiovascular Disease in the Women's Health Initiative Cohorts (JAMA 2009) “Conclusion After a median follow-up of 8.0 and 7.9 years in the clinical trial and observational study cohorts, respectively, the Women's Health Initiative study provided convincing evidence that multivitamin use has little or no influence on the risk of common cancers, CVD, or total mortality in postmenopausal women.”

Multivitamin use and telomere length in women. (Am J Clin Nutr. 2009) “CONCLUSION: This study provides the first epidemiologic evidence that multivitamin use is associated with longer telomere length among women.”

Use of Supplements of Multivitamins, Vitamin C, and Vitamin E in Relation to Mortality. (Am J Epidemiol. 2009)

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