General Cardiovascular

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Cardiovascular - General

General Information

NEWS:

C-Reactive Protein Concentration and Risk of Coronary Heart Disease, Stroke, and Mortality: An Individual Participant Meta-Analysis “Perspective: There is debate about the clinical utility of CRP for risk assessment in cardiovascular disease as well as whether it is a causal relationship or simply a biomarker of risk. This study adds to the abundant literature supporting CRP as a risk marker for cardiovascular events and mortality. And the JUPITER trial provided clinical evidence that it may be useful to risk stratify persons with relatively normal lipid profiles for deciding statin therapy. CRP binds to low-density lipoprotein, and is found in atherosclerotic plaque, suggesting causality. However, this study showing attenuation of attributable risk when corrected for fibrinogen, and recent studies showing no relationship between genetic polymorphisms associated with a higher level of CRP and cardiovascular disease imply that CRP is a risk marker, but not a risk factor for cardiovascular events. And the important saga continues. “

C-Reactive Protein Levels Vary by Race

ED a Red Flag for Heart Attack, Strokes “Erectile dysfunction is an early warning sign of heart disease and may provide a window of opportunity to stave off heart attacks and strokes, according to a review article in the June issue of the International Journal of Clinical Practice. Men with erectile dysfunction typically develop heart-related symptoms within two to three years, and they are at risk of experiencing a cardiac event such as a heart attack or stroke within three to five years, the study shows.”

Erectile Dysfunction a Red Flag for Mortality, Cardiovascular Events

High Resting Heart Rate Means Shorter Life? “Heart disease patients with the lowest heart rate, 59 beats per minute or less, had the least risk of suffering a major cardiac event. Those who had heart rates greater than 78 had a 39 percent increased risk of suffering a major cardiac event, 77 percent increased risk of cardiovascular disease death, and a 65 percent increased risk of all-cause death. They were twice as likely to be hospitalized as those with lower heart rates.”

ARTICLES:

Is White Wine Good For Your Heart?

The Truth About Belly Fat “Study participants who ate all whole grains (in addition to five servings of fruits and vegetables, three servings of low-fat dairy, and two servings of lean meat, fish, or poultry) lost more weight from the abdominal area than another group that ate the same diet, but with all refined grains. "Eating a diet rich in whole grains while reducing refined carbohydrates changes the glucose and insulin response and makes it easier to mobilize fat stores," says study researcher Penny Kris-Etherton, PhD, RD, a distinguished professor of nutritional sciences at Penn State University. "Visceral fat is more metabolically active and easier to lose than subcutaneous fat, especially if you have plenty of it and the right conditions are met, such as the ones in our study."”

JOURNAL ARTICLES:

Association between Psoriasis and Cardiovascular Risk Factors in Korean Patients. (Ann Dermatol. 2010)

Dietary intake of n–3 long-chain polyunsaturated fatty acids and coronary events in Norwegian patients with coronary artery disease (Am J Clin Nutr 2010) “Conclusion: Among Norwegian patients with CAD consuming relatively high amounts of n–3 LCPUFAs and fish, there were no significant trends toward a reduced risk of coronary events or mortality with increasing intakes.”

Low IQ among top heart health risks, study finds “Those who ignored or failed to understand advice about the risks of smoking or benefits of good diet and exercise for heart health would be more likely to be at higher risk, they wrote in a study in the European Journal of Cardiovascular Prevention.”

Moderate red wine consumption and cardiovascular disease risk: beyond the "French paradox". (Semin Thromb Hemost. 2010) “The term FRENCH PARADOX was coined in 1992 to describe the relatively low incidence of cardiovascular disease in the French population, despite a relatively high dietary intake of saturated fats, and potentially attributable to the consumption of red wine. After nearly 20 years, several studies have investigated the fascinating, overwhelmingly positive biological and clinical associations of red wine consumption with cardiovascular disease and mortality. Light to moderate intake of red wine produces a kaleidoscope of potentially beneficial effects that target all phases of the atherosclerotic process, from atherogenesis (early plaque development and growth) to vessel occlusion (flow-mediated dilatation, thrombosis).”

The homocysteine hypothesis: Still relevant to the prevention and treatment of cardiovascular disease? ( 2010) “Thus, instead of concluding that no patients could benefit from homocysteine-lowering treatment, future studies need to clarify: • Whether patients with elevated homocysteine would benefit from such treatment • At what level it would be appropriate to start treatment • The appropriate target homocysteine level with treatment. Particularly given the recent finding that folic acid supplementation may increase cancer risk,63 these questions need closer scrutiny. “

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