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Diabetes Mellitus Type II

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Diabetes

NIH - Diabetes (Medical Encyclopedia) Type 2 diabetes is far more common than type 1 and makes up 90% or more of all cases of diabetes. It usually occurs in adulthood. Here, the pancreas does not make enough insulin to keep blood glucose levels normal, often because the body does not respond well to the insulin. Many people with type 2 diabetes do not know they have it, although it is a serious condition. Type 2 diabetes is becoming more common due to the growing number of older Americans, increasing obesity, and failure to exercise. … Unlike type 1 diabetes, type 2 diabetes may respond to treatment with exercise, diet, and/or oral medications. … Some people with type 2 diabetes find they no longer need medication if they lose weight and increase activity, because when their ideal weight is reached, their own insulin and a careful diet can control their blood glucose levels."

NHS – Diabetes (Video)

NHS - Diabetes: the facts “Symptoms of diabetes The symptoms of both type 1 and type 2 diabetes include: • Increased thirst, and drinking a lot of fluids. • Passing a lot of urine. • Being tired for no reason. • Weight loss. • Genital itching or repeated bouts of thrush. • Slow healing of wounds. • Blurred vision. In type 1 diabetes, symptoms will typically develop over a few weeks and quickly become very obvious. In type 2, symptoms can develop more slowly, over a period of months. Some people with type 2 diabetes have only very mild symptoms, which they believe have other causes. A few people may have no symptoms at all. … Types of diabetes There are two main types of diabetes. • Type 1: in this type, the body can't produce any insulin. This type of diabetes usually occurs before age 40, and accounts for only around 10% of all cases. But it is the most common form of childhood diabetes. • Type 2: this is where the body doesn't make enough insulin, or where the body builds up a resistance to insulin so that it doesn't work effectively. It's the most common form of diabetes (90% of all cases), and is frequently linked with being overweight. One in 10 people in the UK will eventually develop type 2 diabetes.”

Highlighted Articles

Diabetes Seems to Heighten Glaucoma Risk: Regular screenings may help prevent irreversible nerve damage (2008) "A recent study in the journal Ophthalmology found that women with diabetes have about a 70 percent increased risk of developing the most common form of glaucoma -- primary open-angle glaucoma -- compared to women without diabetes."

Researchers report periodontal disease independently predicts new onset diabetes (2008) “These data add a new twist to the association and suggest that periodontal disease may be there before diabetes," said Ryan T. Demmer, PhD, MPH, associate research scientist in the Department of Epidemiology at the Mailman School of Public Health and lead author. "We found that over two decades of follow-up, individuals who had periodontal disease were more likely to develop Type 2 diabetes later in life when compared to individuals without periodontal disease." “

Intake of Fruit, Vegetables, and Fruit Juices and Risk of Diabetes in Women (Diabetes Care 2008) “CONCLUSIONS—Consumption of green leafy vegetables and fruit was associated with a lower hazard of diabetes, whereas consumption of fruit juices may be associated with an increased hazard among women.”

Diabetic Neuropathy--A Review (Nat Clin Pract Neurol. 2007) "Diabetic neuropathy is the most common neuropathy in industrialized countries, and it is associated with a wide range of clinical manifestations. The vast majority of patients with clinical diabetic neuropathy have a distal symmetrical form of the disorder that progresses following a fiber-length-dependent pattern, with sensory and autonomic manifestations predominating. This pattern of neuropathy is associated with a progressive distal axonopathy. Patients experience pain, trophic changes in the feet, and autonomic disturbances. Occasionally, patients with diabetes can develop focal and multifocal neuropathies that include cranial nerve involvement and limb and truncal neuropathies."

Adiposity Compared With Physical Inactivity and Risk of Type 2 Diabetes in Women (Diabetes Care 2007) "CONCLUSIONS—Obesity and physical inactivity independently contribute to the development of type 2 diabetes; however, the magnitude of risk contributed by obesity is much greater than that imparted by lack of physical activity."

Walking for exercise--does three times per week influence risk factors in type 2 diabetes? (Diabetes Res Clin Pract. 2006) "Our results suggest that an increase of regular physical activity equivalent to 45 min of walking 3 days/week may suffice to improve systolic and diastolic blood pressure, lipid metabolism and BMI in patients with type 2 diabetes."

Health Problems That Diabetes Can Cause

Internet Sites

NIH - NIDDK Diabetes

NIH - Diabetes

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Diabetes Mellitus Type II

General Information

NEWS:

Major depression more than doubles risk of dementia among adults with diabetes “The exact manner in which diabetes and depression interact to result in poorer outcomes is not certain. Some studies suggest that a genetic marker for dementia is associated with a faster cognitive decline. Depression may also raise the risk of dementia, the authors noted, because of biological abnormalities linked to this affective illness, including high levels of the stress hormone cortisol, poor regulation in the hypothalamus-pituitary system, or autonomic nervous system problems that can affect heart rate, blood clotting, and inflammatory responses. Depression, they added, might also raise the risk of dementia because of behaviors common in the condition, such as smoking, over-eating, lack of exercise, and difficulty in adhering to medication and treatment regimens. In the current study, patients with both diabetes and major depression were more likely to be female, single, smokers, physically inactive, and treated with insulin. They also had more diabetes complications and a higher body mass index, a ratio calculated from height and weight. However, these differences were controlled for in the analysis and depression remained an important risk factor. Diabetes, the authors noted, is a risk factor for dementia because of blood vessel problems and also may accelerate the decline of Alzheimer's disease. Many factors linked to diabetes might also increase the odds of developing dementia, including tissue damage from high blood sugar levels, episodes of low blood sugar and insulin resistance.”

Nap lovers show higher diabetes rate

Risk of developing dementia in people with diabetes and mild cognitive impairment. (Br J Psychiatry. 2010) “CONCLUSIONS: Diabetes mellitus increases not only the risks of dementia and mild cognitive impairment but also the risk of progression from such impairment to dementia.”

'Silent Strokes' Linked to Kidney Failure in Diabetics

Sleep Apnea May Complicate Diabetes Care

ARTICLES:

Stock Your Kitchen for Diabetes Health

JOURNAL ARTICLES:

Consumption of restaurant foods and incidence of type 2 diabetes in African American women. (Am J Clin Nutr. 2009)

Serum Selenium Concentrations and Diabetes in U.S. Adults: National Health and Nutrition Examination Survey (NHANES) 2003–2004 (Environmental Health Perspectives. 2009) “Most Americans have selenium intake ranging from 60 to 220 < g/day (Combs 2001), well above the recommended dietary allowance of 55 < g/day (Institute of Medicine and Panel on Dietary Antioxidants and Related Compounds 2000; Rayman 2008). This high level of intake, particularly compared with other countries, is attributable to the high soil content of selenium in several areas of the United States, which is eventually incorporated in the food chain (Rayman 2008). Although selenium is required for adequate function of glutathione peroxidase and other selenoproteins, the risk of selenium deficiency in the U.S. general population is negligible. Additional selenium intake at high intake levels does not increase glutathione peroxidase synthesis or activity, but rather increases plasma selenium concentration by the nonspecific incorporation of selenomethionine into plasma proteins (Institute of Medicine and Panel on Dietary Antioxidants and Related Compounds 2000), with unknown health effects. … Because there is a narrow range between selenium intake levels required for selenoprotein synthesis and toxic levels (Institute of Medicine and Panel on Dietary Antioxidants and Related Compounds 2000), these findings raise concerns of possible adverse cardiometabolic effects of high selenium exposure, at least in selenium-replete populations such as the United States. … Conclusions: In U.S. adults, high serum selenium concentrations were associated with higher prevalence of diabetes and higher fasting plasma glucose and glycosylated hemoglobin levels. Given high selenium intake in the U.S. population, further research is needed to determine the role of excess selenium levels in the development or the progression of diabetes.”



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