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Insomnia

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Chronic Insomnia With Objectively Measured Short Sleep Duration Is Associated With Increased Mortality In Men “Compared to men without insomnia who slept for six hours or more, men with chronic insomnia who slept for less than six hours were four times more likely to die during the 14-year follow-up period (odds ratio = 4.33). Results were adjusted for potential confounders such as body mass index, smoking status, alcohol use, depression and obstructive sleep apnea. Further adjustments for hypertension and diabetes had little effect on the elevated mortality risk (OR = 4.00). No significant mortality risk was found in women with insomnia and a short sleep duration of less than six hours (OR = 0.36).”

Poor sleep quality increases inflammation, community study finds “Individuals who reported six or fewer hours of sleep had higher levels of three inflammatory markers: fibrinogen, IL-6 and C-reactive protein. In particular, average C-reactive protein levels were about 25 percent higher (2 milligrams per liter compared to 1.6) in people who reported fewer than six hours of sleep, compared to those reporting between six and nine hours. That difference was still significant even when the data is corrected for known risk factors such as smoking, blood pressure, diabetes and obesity, Morris says. C-reactive protein is used extensively as a marker of inflammation and heart disease risk. People whose C-reactive protein levels are in the upper third of the population (above 3 milligrams per liter) have roughly double the risk of a heart attack, compared with people with lower C-reactive protein levels, according to the American Heart Association and Centers for Disease Control and Prevention.”

ARTICLES:

Insomnia

JOURNAL ARTICLES:

Long-term sleep disturbances in children: A cause of neuronal loss. (Eur J Paediatr Neurol. 2010)

[Management of insomnia and hypersomnia associated with psychiatric disorders]. (Seishin Shinkeigaku Zasshi. 2010)

Prevalence and correlates of insomnia in the Swedish population aged 19-75 years. (Sleep Med. 2010)

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