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Atherosclerosis

:: Jun-Jul 2008


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Clinical Guidelines

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Related InfoMedSearch Topics (2 Selected)

Related Topics - Highlighted Articles

Cardiovascular: Stroke

Diagnosis and prevention of atherosclerotic cerebral infarction. (CNS Spectr. 2005) "Atherosclerotic disease accounts for approximately 25% of ischemic strokes. Atherosclerotic stroke is caused mainly by embolic events from the carotid artery bifurcation or the aortic arch, although intracranial thrombosis can occur, more often in African Americans, Asians, and diabetes patients."


Cardiovascular: Hypertension

Inflammation may be a bridge connecting hypertension and atherosclerosis. (Med Hypotheses. 2005) "Pathogenesis of the atherosclerotic process is deemed as multi-factorial, and characterized by chronic inflammatory response. Although hypertension is known to be one of the most important risk factors for atherosclerosis in causasians, its relative contribution to early atherosclerosis are still unknown. ÄBased on those increasing evidence, we hypothesize that inflammation may be a bridge connecting hypertension and atherosclerosis."

 

Diagnosis, Imaging, and Screening

 

General Information

Pro-inflammatory genetic background and zinc status in old atherosclerotic subjects. (Ageing Res Rev. 2008) “Zinc deficiency has been suggested as an environmental risk factor for AT. With advancing age, the incidence of zinc deficiency increases for several reasons. Among them, dietary intake, malabsorption and genetic background of inflammatory markers may be involved. A crucial contribution may also be played by increased oxidative stress which may lead to the appearance of dysfunctional proteins, including metallothioneins (MT) that are in turn involved in zinc homeostasis. The detection of candidate genes related to inflammation and promoting AT and their reciprocal influence/interaction with zinc status might allow earlier appropriate dietary interventions in genetically susceptible subjects.”

 

Risk Factors

 

Risk Reduction

 

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