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Cervical Cancer

:: Jun-Jul 2008


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View all Treatment articles in our Treatment Report . The most recent articles are listed on top (not in alphabetical order). Click on the Topic on our home page and then the subtopic - Treatment Report. Stay updated on drugs and their side effects, and various other treatments, including exercise, nutrition, and supplements.

Highlighted Article

Repeated Past Article:

Dietary intakes of selected nutrients and food groups and risk of cervical cancer. (Nutr Cancer. 2008) “Our findings suggest that a diet rich in plant-based nutrients may be important in reducing the risk of cervical cancer.”

Clinical Guidelines

AHRQ - Initial management of abnormal cervical cytology (Pap smear) and human papillomavirus (HPV) testing: percentage of adult women diagnosed with initial abnormal cervical cytology of atypical squamous cells of undetermined significance (ASCUS) with high-risk HPV type who have follow-up colposcopy within six months of abnormality identified. (2006)

American Cancer Society Guideline for Human Papillomavirus (HPV) Vaccine Use to Prevent Cervical Cancer and Its Precursors (CA Cancer J Clin 2007)

Guidelines Issued for HPV Use to Prevent Cervical Cancer

NCCN Clinical Practice Guidelines in Oncology: Cervical Cancer Screening (2008)

NGC - American Cancer Society guideline for the early detection of cervical neoplasia and cancer. (2002)

NGC - Cervical cancer. (2003)

NGC - Cervical cancer screening. (2005)

NGC - Cervical cancer screening guideline: October 2006. (2006)

NGC - Cervical cancer: screening recommendations, with algorithms, for managing women with abnormal Pap test results. (2004)

NGC - Cervical screening. (2005)

NGC - GUIDELINE SYNTHESIS SCREENING FOR CERVICAL CANCER

NGC - Human papillomavirus infection. Sexually transmitted diseases treatment guidelines 2002. (2002)

NGC - Management of initial abnormal Pap smear. (2005)

NGC - Primary treatment for locally advanced cervical cancer: concurrent platinum-based chemotherapy and radiation. (2004)

NGC - Role of imaging in cancer of the cervix. (2005)

NGC - SCREENING FOR CERVICAL CANCER (GUIDELINE SYNTHESIS)

NGC - Screening for cervical cancer: recommendations and rationale. (2003)

NGC - Self-collected samples for testing of oncogenic human papillomavirus: a clinical practice guideline. (2006)

Ontario Cervical Screening Evidence-Based Guidelines (2005) Full Report (2005)

Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP) (MMWR 2007)

Internet Sites

Related InfoMedSearch Topics

Related Topics - Highlighted Articles

Sexually Transmitted Diseases (STDs)

CDC - HPV Infection "Genital HPV infection is a sexually transmitted disease (STD) that is caused by human papillomavirus (HPV). Human papillomavirus is the name of a group of viruses that includes more than 100 different strains or types. More than 30 of these viruses are sexually transmitted, and they can infect the genital area of men and women including the skin of the penis, vulva (area outside the vagina), or anus, and the linings of the vagina, cervix, or rectum. ? Some of these viruses are called ?high-risk? types, and may cause abnormal Pap tests. They may also lead to cancer of the cervix, vulva, vagina, anus, or penis. Others are called ?low-risk? types, and they may cause mild Pap test abnormalities or genital warts. Genital warts are single or multiple growths or bumps that appear in the genital area, and sometimes are cauliflower shaped."


Sexually Transmitted Diseases (STDs)

Association of Chlamydia trachomatis with Persistence of High-Risk Types of Human Papillomavirus in a Cohort of Female Adolescents. (Am J Epidemiol. 2005) "Human papillomavirus (HPV) infection is a necessary but not sufficient cause of cervical cancer. While chlamydia infection has been associated with cervical cancer, the meaning of this association remains unclear. The authors' objective was to investigate this association by evaluating whether concurrent genital tract infections are associated with HPV persistence, a precursor to cervical cancer. ? Concurrent infection with C. trachomatis was independently associated with persistence of high-risk HPV types ... Infection with more than one HPV type at the initial visit was also associated with high-risk persistence ... The association between chlamydia infection and cervical cancer may be due to an effect of chlamydia infection on persistence of high-risk HPV."

 

Diagnosis, Imaging, and Screening

Watchful Waiting May Be Appropriate for Some Women With HPV “Cervical HPV infection is not a disease per se but is a marker for potential future cervical cancer, but the risk for cancer after a single-time HPV infection is low, especially in young women, whereas persistent infections with types of carcinogenic HPV are more likely to increase the risk for cervical cancer. … • One-time detection of infection with carcinogenic HPV is associated with a high rate of clearance of 67% by 12 months. • Persistence of carcinogenic HPV infection, in particular HPV-16, is associated with a higher risk for progression to CIN2+, especially in women younger than 30 years. “

 

General Information

Early Sex Doesn't Predict HPV Infection: Study Fuels Debate Over the Best Vaccination Strategy

Human Papillomavirus, Cervical Cancer, and the Vaccines. (Postgrad Med. 2008)

Is viral status needed before vaccination? (Vaccine. 2008)

Persistent Human Papillomavirus Infection and Cervical Neoplasia: A Systematic Review and Meta-Analysis (American Journal of Epidemiology 2008)

Small Cell Cervical Cancer Usually Has Poor Prognosis “Small cell carcinoma of the cervix is rare compared to other cervical cancers, but the outlook for patients with this disease is poor, Utah-based researchers report in the June issue of Obstetrics and Gynecology.”

 

Risk Factors

 

Risk Reduction

 

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