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Fertility - Infertility

:: Jun-Jul 2008


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View all Treatment articles in our Treatment Report . The most recent articles are listed on top (not in alphabetical order). Click on the Topic on our home page and then the subtopic - Treatment Report. Stay updated on drugs and their side effects, and various other treatments, including exercise, nutrition, and supplements.

Highlighted Articles

Being too fat 'can damage sperm' “Obese men have poorer quality sperm, perhaps because too much fat around their testicles causes them to heat up, scientists have suggested. University of Aberdeen researchers looked at the sperm of over 2,000 men in couples having problems conceiving. The heaviest men had a higher proportion of abnormal sperm, as well as other problems. The scientists told a European fertility conference losing weight probably boosted fertility. “

A pilot study associating urinary concentrations of phthalate metabolites and semen quality. (Syst Biol Reprod Med. 2008) “Results suggest that ambient phthalate metabolite concentrations may adversely affect human semen quality.”

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Sexually Transmitted Diseases (STDs)

Chlamydia trachomatis infection in sexually active adolescents and young women. (Med Wieku Rozwoj. 2005) "Sexually active adolescents are at a greater risk for sexually transmitted infections, including Chlamydia trachomatis (ChT). Most inflections are asymptomatic and therefore untreated. Early detection and treatment of cervical chlamydial infections can prevent pelvic inflammatory disease and has a strong protective effect against infertility. Ä RESULTS: The prevalence of ChT genital infection in the studied group was 3.2%. Adolescent females infected by ChT less frequently reported the use of condom and more often did not use any contraception in comparison with the girls without ChT genital infections Ä"


Environmental Health

Smoking and reproduction: The oviduct as a target of cigarette smoke. (Reprod Biol Endocrinol. 2005) "This review considers the role of the oviduct in oocyte pick-up and embryo transport and the evidence that chemicals in both mainstream and sidestream cigarette smoke impair these oviductal functions. Epidemiological data have repeatedly shown that women who smoke are at increased risk for a variety of reproductive problems, including ectopic pregnancy, delay to conception, and infertility."

 

Diagnosis, Imaging, and Screening

 

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Chlamydia trachomatis infection in women with secondary infertility. (Fertil Steril. 2008) “CONCLUSION(S): Prevalence of past chlamydial infection is strongly statistically significant in women with secondary infertility. Current infection was also found statistically significantly in these women. Immunoglobulin G antibody detection is an effective and noninvasive tool for detection of Chlamydia and a more viable option than HSG in a developing country such as India. Screening of women with secondary infertility for C. trachomatis is strongly recommended to allow early therapeutic interventions.”

Coffee 'worsens poor fertility' “Drinking too much coffee can lower the odds of a woman with fertility problems getting pregnant, a study suggests. Dutch researchers followed 9,000 women who had received IVF to see if they fell pregnant naturally. Around one in seven did, but drinking more than four cups of coffee a day cut chances of conceiving by around 26%. Experts said the findings, presented to a European conference, only applied to women with poor fertility who wanted to maximise their chances of pregnancy. “

Diabetes Linked To Male Infertility; Excess Sugars In The Body Have Direct Effect On Sperm Quality

Evidence that obesity alters the quality of oocytes and embryos. (Pathophysiology. 2008) “Infertility is more common in overweight and obese women, with reproductive impairments occurring at many levels of the hypothalamic-ovarian-uterine axis. These impairments lead primarily to longer times to conception and decreased pregnancy rates and have resulted in increasing numbers of overweight and obese women seeking assisted reproduction technologies, such as in vitro fertilization or IVF. Even after undertaking IVF procedures obese women have decreased pregnancy rates compared to moderate weight women, suggesting there may be intrinsic differences in the oocytes of these patients.”

Human semen quality and sperm DNA damage in relation to urinary metabolites of pyrethroid insecticides. (Hum Reprod. 2008) “CONCLUSIONS We found evidence for reduced semen quality and increased sperm DNA damage in relation to urinary metabolites of pyrethroid insecticides. These findings may be of concern due to increased pyrethroid use and prevalent human exposure.”

Soy Linked to Low Sperm Count “Eating half a serving of soy food a day lowers sperm concentrations and may play a role in male infertility, particularly in obese men, Harvard University researchers report. The reason for this relationship between soy and sperm count isn't clear. However, researchers speculate that soy increases estrogen activity, which may have a negative affect on sperm production and also interfere with other hormonal signals. "There have been a lot of interest in estrogen and isoflavones in particular and a potential relationship to fertility and other reproductive disorders," said lead researcher Dr. Jorge Chavarro, a research fellow in the department of nutrition at the Harvard School of Public Health. Research in animals has shown that isoflavones and estrogen can have a potentially negative affect on reproduction, including decreased fertility, Chavarro said. However, there is very little evidence of how these findings apply to humans, he said. … "When patients are overweight, the fat tissue converts male hormones to more female hormones," Sadeghi-Nejad said. "So, it is possible that the combination of this estrogenic source [soy] and the extra internal estrogen that is caused by the conversion of androgen to estrogen through the fat has a more deleterious effect in that group of patients." “

 

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