:: Jun-Jul 2008

Welcome to our Monthly Online Newsletter!

View all Treatment articles in our Treatment Report . The most recent articles are listed on top (not in alphabetical order). Click on the Topic on our home page and then the subtopic - Brain Injury Daily Treatment Report and Spinal Injury Daily Report. Stay updated on drugs and their side effects, and various other treatments, including exercise, nutrition, and supplements.

Highlighted Article

Clinical Guidelines

CDC - Concussion in High School Sports Guide for Coaches (2005)

NGC - Assessment: Glasgow Coma Scale score. In: Guidelines for the prehospital management of severe traumatic brain injury, second edition. (2007)

NGC - Assessment: oxygenation and blood pressure. In: Guidelines for the prehospital management of severe traumatic brain injury, second edition. (2007)

NGC - Assessment: pupil examination. In: Guidelines for the prehospital management of severe traumatic brain injury, second edition. (2007)

NGC - Concussion, mild head injury. (2005)

NGC - Early management of patients with a head injury. A national clinical guideline. (2000)

NGC - Guidelines for prehospital management of traumatic brain injury. (2000)

NGC - Head injury in children. (2001)

NGC - Head injury: triage, assessment, investigation and early management of head injury in infants, children and adults. (2003)

NGC - Head trauma. (2006)

NGC - Outcomes following traumatic spinal cord injury. (1999)

NGC - (1) Part I. Guidelines for the management of severe traumatic brain injury. In: Management and prognosis of severe traumatic brain injury. (2) Update notice. Guidelines for the management of severe traumatic brain injury: cerebral perfusion pressure. (2003)

NGC - Part II. Early indicators of prognosis in severe traumatic brain injury. In: Management and prognosis of severe traumatic brain injury. (2000)

NGC - Practice management guidelines for the management of mild traumatic brain injury. (2000)

NGC - Practice parameter: antiepileptic drug prophylaxis in severe traumatic brain injury: report of the Quality Standards Subcommittee of the American Academy of Neurology. (2003)

NGC - Preservation of upper limb function following spinal cord injury: a clinical practice guideline for health-care professionals. (2005)

NGC - Pressure ulcer prevention and treatment following spinal cord injury. (2000)

NGC - Prevention of thromboembolism in spinal cord injury. (1999)

NGC - Traumatic brain injury: diagnosis, acute management and rehabilitation. (2006)

NICE - Head injury: Triage, assessment, investigation and early management of head injury in infants, children and adults (2003)

Traumatic Brain Injury

Internet Sites

Featured site

NIH - Medical Encyclopedia Head injury

Brain Concussion

CDC - Learn to Prevent & Recognize Concussions

NIH - Head and Brain Injuries

NIH - Medical Encyclopedia Concussion

NIH - NINDS Traumatic Brain Injury Information Page

Brain Injury

NIH - Head and Brain Injuries

NIH - NIDCD Traumatic Brain Injury: Cognitive and Communication Disorders

NIH - NINDS Traumatic Brain Injury Information Page

Spinal Cord Injury

NIH - Medical Encyclopedia Babinski's reflex

NIH - Medical Encyclopedia Spinal cord injury

NIH - Medical Encyclopedia Spinal cord trauma

NIH - Medical Encyclopedia Spinal/neck injury

NIH - Organization Contact Information

NIH - Spinal Cord Injuries

NIH - Spinal Cord Injury Information Page

NIH - Spinal Cord Injury: Emerging Concepts

NIH - Spinal Cord Injury: Hope Through Research

Related Topics - Highlighted Articles

Antioxidants - Oxidative Stress

Role of oxidative damage in the pathogenesis of viral infections of the nervous system. (Histol Histopathol. 2005) "Oxidative stress, primarily due to increased generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS), is a feature of many viral infections. Ä Oxidative injury is a component of acute encephalitis caused by herpes simplex virus type 1 and reovirus, neurodegenerative disease caused by human immunodeficiency virus and murine leukemia virus, and subacute sclerosing panencephalitis caused by measles virus."

Supplements - Nutrition

Does melatonin protect or treat brain damage from traumatic oxidative stress? (Exp Brain Res. 2005) "In conclusion, the data indicate that melatonin protects against free radical-mediated oxidative changes in brain tissue by boosting antioxidant enzymes, and in particular lowering lipid peroxidation Ä"

In this newsletter:

Brain Concussion
Brain Injury
NeuroDegeneration
NeuroProtection
Spinal Cord Injury

	Brain Concussion
Men And Women With History Of Concussion Mend Differently, Study Finds

	Brain Injury
Outcome and Predictors of Functional Recovery 5 Years Following Pediatric Traumatic Brain Injury (TBI) (Journal of Pediatric Psychology 2008) “Conclusion Children who sustain a severe TBI in early childhood are at greatest risk of long-term impairment in day-to-day skills in the long-term postinjury.” Protecting the brain from spiral of damage

	NeuroDegeneration

	NeuroProtection
Oral administration of grape polyphenol extract ameliorates cerebral ischemia/reperfusion-induced neuronal damage and behavioral deficits in gerbils: comparison of pre- and post-ischemic administration. (J Nutr Biochem. 2008) “These findings indicate that oral GPE intake may confer protection against I/R injury and emphasize that early intervention may be an effective therapeutic measure for ameliorating brain injury in stroke.” Protective effect of quercetin in primary neurons against Abeta(1-42): relevance to Alzheimer's disease. (J Nutr Biochem. 2008) Vitamin D and neurocognitive dysfunction: Preventing "D"ecline? (Mol Aspects Med. 2008) “Vitamin D exhibits functional attributes that may prove neuroprotective through antioxidative mechanisms, neuronal calcium regulation, immunomodulation, enhanced nerve conduction and detoxification mechanisms. Compelling evidence supports a beneficial role for the active form of vitamin D in the developing brain as well as in adult brain function.”

	Spinal Cord Injury