:: Jun-Jul 2008

Welcome to our Monthly Online Newsletter!

View all Treatment articles in our Treatment Report . The most recent articles are listed on top (not in alphabetical order). Click on the Topic on our home page and then the subtopic - Treatment Report. Stay updated on drugs and their side effects, and various other treatments, including exercise, nutrition, and supplements.

How Frequent is Chronic Multiyear Delusional Activity and Recovery in Schizophrenia: A 20-Year Multi-follow-up. (Schizophr Bull. 2008) “Twenty-six percent of the patients with schizophrenia were delusional at all follow-ups over the 20 years. Overall, 57% had frequently recurring or persistent delusions. A subgroup of over 25% of the schizophrenia patients had no delusional activity at any of the 6 follow-ups over 20 years. Schizophrenia patients with posthospital delusional activity had increased work disability (P < .05). Delusions that persisted after the acute phase in schizophrenia patients predicted a lower likelihood of future global recovery (P < .01). In conclusion, slightly over half of modern-day schizophrenia patients are vulnerable to frequent or "chronic" delusional activity after the acute phase. Schizophreniform patients and other types of psychotic disorders are vulnerable to posthospital delusional activity, but less frequently, less severely, and more episodically. Delusional activity is associated with work disability. Internal factors such as good premorbid developmental achievements and favorable prognostic factors are protective factors that reduce the probability of chronic multiyear, delusional activity in schizophrenia (P < .01).”

NGC - Management of persons with psychoses. (2004)

NGC - Practice parameter for the assessment and treatment of children and adolescents with schizophrenia. (2000)

NGC - Practice guideline for the treatment of patients with schizophrenia. Second edition. (2004)

NGC - Schizophrenia (2003)

NGC - Schizophrenia: core interventions in the treatment and management of schizophrenia in primary and secondary care. (2002)

Featured site

NIH - Schizophrenia

NIH - Medical Encyclopedia Schizophrenia

NIH - NIMH Schizophrenia

NIH - NIMH When Someone Has Schizophrenia

NIH - Schizophrenia Resources

Online Schizophrenia resource

Bipolar Disorder

Bipolar Disorder

Genetic models of schizophrenia and bipolar disorder Overlapping inheritance or discrete genotypes? (Eur Arch Psychiatry Clin Neurosci. 2005) "We review current evidence of the genetic relationship between schizophrenia and affective disorders, mainly bipolar disorder (the various genetic research methods have been particularly applied to bipolar disorder). Recent family and twin studies reveal a growing consistency in demonstrating cosegregation between both disorders Ä"

Bipolar Disorder

Familial overlap between bipolar disorder and psychotic symptoms in a Canadian cohort. (Can J Psychiatry. 2005) "BACKGROUND: Although they were once considered separate nosologic entities, there is current interest in the etiologic overlap between bipolar disorder (BD) and schizophrenia. Ä CONCLUSIONS: Findings from this sample support etiologic theories arguing for a shared but nonspecific genetic etiology for BD and schizophrenia Ä"