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Aging - Anti-Aging

:: June 2009


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View all Treatment articles in our Treatment Report . The most recent articles are listed on top (not in alphabetical order). Click on the Topic on our home page and then the subtopic - Treatment Report. Stay updated on drugs and their side effects, and various other treatments, including exercise, nutrition, and supplements.

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Alzheimer's Disease - Dementia

Incidence and etiology of dementia in a large elderly Italian population (NEUROLOGY 2005) "Conclusions: In this Italian population-based cohort, incidence of dementia increased with age, and Alzheimer disease (AD) was the most frequent type of dementia. Poor education was associated with a higher risk of AD."


Antioxidants and Oxidative Stress

Oxidative stress on mitochondrial antioxidant defense system in the aging process: role of DL-alpha-lipoic acid and L-carnitine. (Clin Chim Acta. 2005) "BACKGROUND: Oxidative damage is hypothesized to accumulate throughout the lifetime of an organism, eventually giving rise to aging. The mitochondria may be the primary cellular source and target of endogenous ROS as they are produced as a normal byproduct of the electron transport system. ƒ CONCLUSION: Co-supplementation of lipoic acid with carnitine has a beneficial effect in reversing the age-related abnormalities seen in aging. This effect was associated with the decrease in free radical production and rise in antioxidant levels by carnitine and lipoic acid, thereby lowering oxidative stress."

 

Anti-Aging

 

General Information

Age, neuropathology, and dementia. (N Engl J Med. 2009)

Effects on balance, falls, and bone mineral density of a home-based exercise program without home visits in community-dwelling elderly women: a randomized controlled trial. (J Physiol Anthropol. 2009)

Elevated C-reactive protein levels are associated with prevalent dementia in the oldest-old (The Lancet 2009) “Background C-reactive protein (CRP) is a nonspecific marker of inflammation that is increased in the brain and serum of patients with Alzheimer's disease (AD), and has been associated with increased risk of developing dementia. Inflammation increases with age, and the number of people reaching age 90 years and older is growing, making the association between inflammation and dementia increasingly relevant. Using a cross-sectional design, we examined whether high levels of serum CRP are associated with increased odds of prevalent dementia in the oldest-old.”

For Men Over 50, Odds of Eye Discomfort Increases “Aside from discomfort, dry eye can also cause blurry or double vision. Some people get relief by drinking more water to relieve mild dehydration, switching medications, discontinuing wearing contact lenses or by using artificial tears sold over-the-counter at drugstores. Physicians may also prescribe anti-inflammatory eye drops for patients with severe dry eyes.”

High Fruit and Vegetable Intake is Positively Correlated with Antioxidant Status and Cognitive Performance in Healthy Subjects. (J Alzheimers Dis. 2009) “Healthy subjects of any age with a high daily intake of fruits and vegetables have higher antioxidant levels, lower levels of biomarkers of oxidative stress, and better cognitive performance than healthy subjects of any age consuming low amounts of fruits and vegetables. Modification of nutritional habits aimed at increasing intake of fruits and vegetables should be encouraged to lower prevalence of cognitive impairment in later life.”

Inner Ear Balance Disorder May Put a Third of Adults at Risk for Falls “More than a third of older adults may unknowingly have an inner ear balance disorder that puts them at high risk of potentially disabling falls. A new study shows that 35% of American adults 40 and older have vestibular dysfunction of the inner ear, which hampers their sense of balance control. People with symptoms of vestibular dysfunction were eight times more likely to experience a fall. Researchers say falls in the elderly are among the most deadly, disabling, and costly health problems in the U.S.”

The same annual dose of 292 000 IU of vitamin D(3) (cholecalciferol) on either daily or four monthly basis for elderly women: 1-year comparative study of the effects on serum 25(OH)D(3) concentrations and renal function. (Clin Endocrinol (Oxf). 2009)

 

Imaging
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