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Aging - Anti-Aging

:: January 2012


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Alzheimer's Disease - Dementia

Incidence and etiology of dementia in a large elderly Italian population (NEUROLOGY 2005) "Conclusions: In this Italian population-based cohort, incidence of dementia increased with age, and Alzheimer disease (AD) was the most frequent type of dementia. Poor education was associated with a higher risk of AD."


Antioxidants and Oxidative Stress

Oxidative stress on mitochondrial antioxidant defense system in the aging process: role of DL-alpha-lipoic acid and L-carnitine. (Clin Chim Acta. 2005) "BACKGROUND: Oxidative damage is hypothesized to accumulate throughout the lifetime of an organism, eventually giving rise to aging. The mitochondria may be the primary cellular source and target of endogenous ROS as they are produced as a normal byproduct of the electron transport system. ƒ CONCLUSION: Co-supplementation of lipoic acid with carnitine has a beneficial effect in reversing the age-related abnormalities seen in aging. This effect was associated with the decrease in free radical production and rise in antioxidant levels by carnitine and lipoic acid, thereby lowering oxidative stress."

 

Anti-Aging

'Exergaming' Helps Older Adults Improve Cognitive Function

Fish oil plus exercise may do older muscles good

Mediterranean Diet Gives Longer Life, Swedish Study Suggests

Music Training Has Biological Impact On Aging Process

The effect of tongue exercise on serotonergic input to the hypoglossal nucleus in young and old rats. (J Speech Lang Hear Res. 2012) “Breathing and swallowing problems affect elderly people and may be related to age-associated tongue dysfunction. Hypoglossal motoneurons that innervate the tongue receive a robust, excitatory serotonergic (5HT) input and may be affected by aging. We used a rat model of aging and progressive resistance tongue exercise to determine if age-related alterations in 5HT inputs to the hypoglossal nucleus can be modifed. … Tongue exercise resulted in increased maximum tongue forces at all ages. There was a statistically significant increase in 5HT immunoreactivity in the hypoglossal nucleus in exercised, young rats, but only in the caudal third of the nucleus, and primarily in the ventral half.”

 

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