:: January 2012

Welcome to our Monthly Online Newsletter!

View all Treatment articles in our Treatment Report . The most recent articles are listed on top (not in alphabetical order). Click on the Topic on our home page and then the subtopic - Treatment Report. Stay updated on drugs and their side effects, and various other treatments, including exercise, nutrition, and supplements.

Highlighted Articles

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Clinical Guidelines

Global Guideline for Type 2 Diabetes

New AACE Guidelines for Prediabetes Management

NGC - Adult diabetes clinical practice guidelines. (2004)

NGC - American Association of Clinical Endocrinologists medical guidelines for clinical practice for the management of diabetes mellitus. Nutrition and diabetes. (2007)

NGC - American Association of Clinical Endocrinologists medical guidelines for clinical practice for the management of diabetes mellitus. Prevention of type 2 diabetes mellitus. (2007)

NGC - American Association of Clinical Endocrinologists medical guidelines for clinical practice for the management of diabetes mellitus. Screening and diagnosis. (2007)

NGC - Diabetes mellitus. (2005)

NGC - Diabetes mellitus. (2006)

NGC - Diabetes Mellitus Algorithm D: Core (2003)

NGC - Diabetes Mellitus Algorithm S: Screening and Prevention (2003)

NGC - Diabetes nutrition recommendations for health care institutions. (2004)

NGC - Diabetic foot disorders: a clinical practice guideline. (2006)

NGC - Diabetic retinopathy. (2008)

NGC - Diagnosis and classification of diabetes mellitus. (2005)

NGC - Diagnosis and management of type 2 diabetes mellitus in adults. (2008)

NGC - Guidelines on diabetes, pre-diabetes, and cardiovascular diseases. (2007)

NGC - Hyperglycemic crises in diabetes. (2004)

NGC - Inpatient management guidelines for people with diabetes. (2004)

NGC - Management of type 2 diabetes mellitus. (2004)

NGC - Nutrition principles and recommendations in diabetes. (2004)

NGC - Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association. (2008)

NGC - Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association. (2007)

NGC - Recommendations for management of diabetes in Vermont. (2004)

NGC - Screening for type 2 diabetes mellitus in adults: U.S. Preventive Services Task Force recommendation statement. (2008)

NGC - Screening for type 2 diabetes mellitus to prevent vascular complications: updated recommendations from the Canadian Task Force on Preventive Health Care. (2005)

NGC - Standards of medical care in diabetes. IV. Prevention/delay of type 2 diabetes. (2008)

NGC - Standards of medical care in diabetes. I. Classification and diagnosis. (2007)

NGC - Standards of medical care in diabetes. II. Screening for diabetes. (2007)

NGC - Standards of medical care in diabetes. III. Detection and diagnosis of gestational diabetes mellitus (GDM). (2007)

NGC - Standards of medical care in diabetes. IV. Prevention/delay of type 2 diabetes. (2007)

NGC - Standards of medical care in diabetes. V. Diabetes care. (2007)

NGC - Standards of medical care in diabetes. VI. Prevention and management of diabetes complications. (2007)

NGC - Wisconsin essential diabetes mellitus care guidelines. (2004)

Revised Nutrition Guidelines for Diabetes Prevention Stress Weight Control, Exercise

Internet Sites

Related Topics - Highlighted Articles

Diet and Health

Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. (Am J Clin Nutr. 2005) "BACKGROUND: Obesity is a strong risk factor for type 2 diabetes. However, few studies have compared the predictive power of overall obesity with that of central obesity. The cutoffs for waist circumference (WC) and waist-to-hip ratio (WHR) as measures of abdominal adiposity remain controversial. OBJECTIVE: The objective was to compare body mass index (BMI), WC, and WHR in predicting type 2 diabetes. ? CONCLUSIONS: Both overall and abdominal adiposity strongly and independently predict risk of type 2 diabetes. WC is a better predictor than is WHR. The currently recommended cutoff for WC of 102 cm for men may need to be reevaluated; a lower cutoff may be more appropriate."

Fitness and Exercise

Effects of exercise training on glucose homeostasis: the HERITAGE Family Study. (Diabetes Care. 2005) "OBJECTIVE: To determine the effect of a 20-week endurance training program in healthy, previously sedentary participants on measures derived from an intravenous glucose tolerance test (i.v.GTT). ? CONCLUSIONS: Although the effects of structured regular exercise were highly variable, there were improvements in virtually all i.v.GTT-derived variables. In the absence of substantial weight loss, regular exercise is required for sustained improvements in glucose homeostasis."

In this newsletter:

Diagnosis, Imaging, and Screening
General Information
Risk Factors
Risk Reduction

	Diagnosis, Imaging, and Screening

	General Information
Age at menarche is associated with prediabetes and diabetes in women (aged 32-81 years) from the general population: the KORA F4 Study. (Diabetologia. 2011) Is the metabolic syndrome caused by a high fructose, and relatively low fat, low cholesterol diet? (Arch Med Sci. 2011) “The metabolic syndrome (MetS) is manifested by a lipid triad which includes elevated serum triglycerides, small LDL particles, and low high-density lipoprotein (HDL) cholesterol, by central obesity (central adiposity), insulin resistance, glucose intolerance and elevated blood pressure, and it is associated with an increased risk of type 2 diabetes and coronary heart disease. We have developed a new hypothesis regarding MetS as a consequence of a high intake in carbohydrates and food with a high glycemic index, particularly fructose, and relatively low intake of cholesterol and saturated fat. … Fructose also leads to increased levels of advanced glycation end products. The macrophages exposed to advanced glycation end products become dysfunctional and, on entry into the artery wall, contribute to plaque formation and thrombosis.” NGC - Wisconsin diabetes mellitus essential care guidelines. (2011)

	Risk Factors
Excess Body Mass Index-Years, a Measure of Degree and Duration of Excess Weight, and Risk for Incident Diabetes (Arch Pediatr Adolesc Med 2012)

	Risk Reduction